High-resolution 7T MR imaging of the motor cortex in amyotrophic lateral sclerosis
M Cosottini, G Donatelli, M Costagli… - American journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Amyotrophic lateral sclerosis is a progressive motor
neuron disorder that involves degeneration of both upper and lower motor neurons. In …
neuron disorder that involves degeneration of both upper and lower motor neurons. In …
Semiautomated evaluation of the primary motor cortex in patients with amyotrophic lateral sclerosis at 3T
G Donatelli, A Retico, EC Ienco… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Amyotrophic lateral sclerosis is a neurodegenerative
disease involving the upper and lower motor neurons. In amyotrophic lateral sclerosis …
disease involving the upper and lower motor neurons. In amyotrophic lateral sclerosis …
[HTML][HTML] Magnetic susceptibility in the deep layers of the primary motor cortex in amyotrophic lateral sclerosis
M Costagli, G Donatelli, L Biagi, EC Ienco… - NeuroImage: Clinical, 2016 - Elsevier
Abstract Amyotrophic Lateral Sclerosis (ALS) is a progressive neurological disorder that
entails degeneration of both upper and lower motor neurons. The primary motor cortex (M1) …
entails degeneration of both upper and lower motor neurons. The primary motor cortex (M1) …
[HTML][HTML] Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: correlating 7 tesla MRI and pathology
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder
characterized by cortical and spinal motor neuron dysfunction. Routine magnetic resonance …
characterized by cortical and spinal motor neuron dysfunction. Routine magnetic resonance …
Histological–MRI correlation in the primary motor cortex of patients with amyotrophic lateral sclerosis
MD Meadowcroft, NJ Mutic, DC Bigler… - Journal of magnetic …, 2015 - Wiley Online Library
Purpose To establish the relationship between ALS histopathology and quantitative MRI
metrics. Materials and Methods ALS patients (N= 8) in advanced stages of the disease were …
metrics. Materials and Methods ALS patients (N= 8) in advanced stages of the disease were …
Magnetization transfer imaging demonstrates a distributed pattern of microstructural changes of the cerebral cortex in amyotrophic lateral sclerosis
M Cosottini, I Pesaresi, S Piazza… - American journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: To date, damage of the cerebral cortex neurons in ALS
was investigated by using conventional MR imaging and proton MR spectroscopy. We …
was investigated by using conventional MR imaging and proton MR spectroscopy. We …
A potential biomarker in amyotrophic lateral sclerosis: can assessment of brain iron deposition with SWI and corticospinal tract degeneration with DTI help?
R Sheelakumari, M Madhusoodanan… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Iron-mediated oxidative stress plays a pivotal role in the
pathogenesis of amyotrophic lateral sclerosis. This study aimed to assess iron deposition …
pathogenesis of amyotrophic lateral sclerosis. This study aimed to assess iron deposition …
Amyotrophic lateral sclerosis: T2 shortening in motor cortex at MR imaging.
H Oba, T Araki, K Ohtomo, S Monzawa, G Uchiyama… - Radiology, 1993 - pubs.rsna.org
PURPOSE: To determine whether decreased signal intensity of the motor cortex (T2
shortening) at magnetic resonance (MR) imaging is a useful finding for supporting the …
shortening) at magnetic resonance (MR) imaging is a useful finding for supporting the …
Low signal intensity in motor cortex on susceptibility-weighted MR imaging is correlated with clinical signs of amyotrophic lateral sclerosis: a pilot study
H Endo, K Sekiguchi, H Shimada, T Ueda, H Kowa… - Journal of …, 2018 - Springer
There is no reliable objective indicator for upper motor neuron dysfunction in amyotrophic
lateral sclerosis (ALS). To determine the clinical significance and potential utility of magnetic …
lateral sclerosis (ALS). To determine the clinical significance and potential utility of magnetic …
A distinct MR imaging phenotype in amyotrophic lateral sclerosis: correlation between T1 magnetization transfer contrast hyperintensity along the corticospinal tract …
G Carrara, C Carapelli, F Venturi… - American journal …, 2012 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: In the search for a diagnostic marker in ALS, we focused
our attention on the hyperintense signal intensity in T1 MTC MR images along the CST …
our attention on the hyperintense signal intensity in T1 MTC MR images along the CST …
