Recent pathologic and MR imaging studies have challenged the classic view of MS as a
chronic inflammatory-demyelinating condition affecting solely the WM of the central nervous …

Multiple sclerosis (MS) is a chronic, disabling, and unpredictable disease of the human
central nervous system (CNS), histologically characterized by multifocal areas of …

Conventional magnetic resonance imaging (cMRI) has greatly improved our ability to
diagnose multiple sclerosis (MS) and to monitor its evolution, either natural or modified by …

The evidence suggesting a role of extensive cortical demyelization and atrophy in
progressive multiple sclerosis is rapidly increasing. Although conventional magnetic …

Magnetic resonance imaging (MRI) is a sensitive technique in the detection and follow-up of
multiple sclerosis (MS) lesions. However, the pathologic basis of these changes is poorly …

The hallmark of multiple sclerosis (MS) pathology is the presence of inflammatory
demyelinated lesions distributed throughout the CNS. Along with more diffuse tissue …

Conventional magnetic resonance imaging (MRI) has routinely been used to improve the
accuracy of multiple sclerosis (MS) diagnosis and prognosis. Metrics derived from …

Although conventional magnetic resonance imaging (cMRI) is widely used for diagnosing
multiple sclerosis (MS) and monitoring disease activity and evolution, the correlation …

Classically multiple sclerosis (MS) has been regarded as an auto‐immune disease of the
white matter in the central nervous system leading to severe disability over the course of …

In this review, we summarize advances in knowledge derived from the application of
magnetic resonance imaging (MRI)-based techniques to patients with multiple sclerosis …