Cerebellar long-term depression: characterization, signal transduction, and functional roles

M Ito - Physiological reviews, 2001 - journals.physiology.org
… In contrast, each PC comes into contact with only one CF via numerous discrete synaptic
junctions formed on stubby dendritic spines (424). Multiple innervation of a PC by CFs occurs …

Cerebellar circuitry as a neuronal machine

M Ito - Progress in neurobiology, 2006 - Elsevier
… are injected into the midbrain ventricle of mouse embryos on different embryonic days
between E10.5 and E12.5, virally infected cerebellar progenitor cells develop into Purkinje cells. …

Long-term depression

M Ito - Annual review of neuroscience, 1989 - annualreviews.org
… cortex forms a modifiable side path into a reflex arc or into a command signal pathway for …
Ito, M. 1977. Neuronal events in the cer ebellar flocculus associated with an adap tive …

[HTML][HTML] Decreased histone deacetylase activity in chronic obstructive pulmonary disease

K Ito, M Ito, WM Elliott, B Cosio… - … England Journal of …, 2005 - Mass Medical Soc
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic
airway inflammation that is greater in patients with advanced disease. We asked whether there …

[HTML][HTML] In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses

…, M Ito, R Takano, K Iwatsuki-Horimoto, M Shimojima… - Nature, 2009 - nature.com
Influenza A viruses cause recurrent outbreaks at local or global scale with potentially severe
consequences for human health and the global economy. Recently, a new strain of …

[PDF][PDF] The translation inhibitor rocaglamide targets a bimolecular cavity between eIF4A and polypurine RNA

…, SN Floor, K Fujiwara, M Mito, K Dodo, M Sodeoka… - Molecular cell, 2019 - cell.com
A class of translation inhibitors, exemplified by the natural product rocaglamide A (RocA),
isolated from Aglaia genus plants, exhibits antitumor activity by clamping eukaryotic translation …

[HTML][HTML] Randomized trial of TAS-102 for refractory metastatic colorectal cancer

…, F Benedetti, H Mizuguchi, L Makris, M Ito… - … England Journal of …, 2015 - Mass Medical Soc
Background Early clinical trials conducted primarily in Japan have shown that TAS-102, an
oral agent that combines trifluridine and tipiracil hydrochloride, was effective in the treatment …

[HTML][HTML] Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

M Amano, M Ito, K Kimura, Y Fukata, K Chihara… - Journal of Biological …, 1996 - ASBMB
… An aliquot (80 µl) of the reaction mixture was added into the stop solution (1.3% charcoal,
0.12 M NaH 2 PO 4 , and 0.33 M perchloric acid) and filtrated. Inorganic phosphate that was …

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

…, M Ito, M Amano, K Chihara, Y Fukata, M Nakafuku… - Science, 1996 - science.org
… MBS, we cloned the complementary DNA encoding rat MBS into pEF-BOS-Myc to yield pEF-…
We thank M. Fujioka and J. Tanaka for preparing polyclonal antibodies to MBS and the 20-…

[BOOK][B] The cerebellum and neural control

M Itō - 1984 - books.google.com
… In the light of these advances, the first aim of this monograph is to review new data obtained
during the past fifteen years and incorporate them into concepts of the cerebellar neuronal …