BACKGROUND AND PURPOSE: Voxel-based morphometry (VBM) has proved a powerful
method to detect subtle changes of gray matter (GM) at the group level but the role of VBM …

BACKGROUND AND PURPOSE: VBM is increasingly used in the study of
neurodegeneration, and recently there has been interest in its potential as a biomarker …

Despite widespread application to human imaging, voxel-based morphometry (VBM), where
images are compared following grey matter (GM) segmentation, is seldom used in mice …

The striatum, a subcortical structure, is the principal target of the neurodegenerative process
in Huntington's disease (HD). The measurement of striatal atrophy using the bicaudate ratio …

Objectives: To analyse grey matter changes in early stages of Huntington's disease using
magnetic resonance imaging (MRI) and the technique of voxel based morphometry (VBM) …

Voxel Based Morphometry (VBM) studies typically involve a comparison between groups of
individuals; this approach however does not allow inferences to be made at the level of the …

Recent morphometric MRI studies have investigated brain volume abnormalities associated
with the diagnosis of Alzheimer's disease (AD) using voxel-based morphometry (VBM). This …

Background and objectives: Regional cerebral atrophy occurs in carriers of the Huntington's
disease (HD) gene mutation before clinical diagnosis is possible. The current inability to …

Structural neuroimaging studies are of great interest for neuroscientists, which are reflected
in the rising number of papers using voxel-based morphometry (VBM). One major step in …

Background: Most clinical symptoms of Huntington disease (HD) have been attributed to
striatal degeneration, but extrastriatal degeneration may play an important role in the clinical …