… include new-onset epilepsy, focal deficits (such as pareses or sensory disturbances),
neurocognitive impairment, and symptoms and signs of increased intracranial pressure. The …

Glioblastomas are the most common form of malignant primary brain tumor and an important
cause of morbidity and mortality. In recent years there have been important advances in …

The European Association for Neuro-Oncology guideline provides recommendations for the
clinical care of adult patients with astrocytic and oligodendroglial gliomas, including …

Accurate pathological diagnosis is crucial for optimal management of patients with cancer.
For the approximately 100 known tumour types of the central nervous system, standardization …

Astrocytic brain tumours, including glioblastomas, are incurable neoplasms characterized
by diffusely infiltrative growth. Here we show that many tumour cells in astrocytomas extend …

Trastuzumab deruxtecan is an antibody–drug conjugate with high extracranial activity in
human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer. We …

Although meningiomas are the most common intracranial tumours, the level of evidence to
provide recommendations for the diagnosis and treatment of meningiomas is low compared …

… Preoperative cognitive deficits in meningioma patients might be the result of anatomical
localization, and elevated intracranial pressure caused by the tumor itself or by tumor-related …

Background The WHO classification of brain tumours describes 15 subtypes of meningioma.
Nine of these subtypes are allotted to WHO grade I, and three each to grade II and grade III. …

Assessment of the immune response to tumors is growing in importance as the prognostic
implications of this response are increasingly recognized, and as immunotherapies are …