In excitatory synapses of the brain, specific receptors in the postsynaptic membrane lie ready
to respond to the release of the neurotransmitter glutamate from the presynaptic terminal. …

… We are grateful to Kristen M. Harris for providing EM sections of brain and 3D reconstructions
of spines for Figure 1 and to Tom Reese and Xiaobing Chen for providing EM images of …

… PSD-95 shows significantly different binding specificity for C-terminal sequences than do
the individual PDZ1 and PDZ2 domains (M Niethammer, M Sheng, unpublished observations). …

We performed a genome-wide association study (GWAS) of systemic lupus erythematosus (SLE)
in a Chinese Han population by genotyping 1,047 cases and 1,205 controls using …

The mechanism by which Ca 2+ mediates gene induction in response to membrane depolarization
was investigated. The adenosine 3′,5′-monophosphate (cAMP) response element…

The logistic transformation applied to a d-dimensional normal distribution produces a
distribution over the d-dimensional simplex which can sensibly be termed a logistic-normal …

… Feger and M. Hattori for help with antibody preparation, and B, Zhao, CL. Huang and M.
Stryker for critical reading of the manuscript. This work was supported by the Silvio Conte Center …

… (M–U) Cultured hippocampal slices were transfected with GFP and MitoDsRed, plus wild-type
Drp1 or Drp1-K38A. Images show segments of apical dendrites of CA1 pyramidal neurons …

… Bargmann for plasmids and for sharing unpublished results, M. Chalfie for gfp plasmids,
and B. Sawin and the rnembers of the Ruvkun and JMK labs for comments on the manuscript. …

Dendritic spines are tiny protrusions that receive excitatory synaptic input and compartmentalize
postsynaptic responses. Heterogeneous in size and shape, and modifiable by activity …