Background Treatment options for recurrent glioblastoma are scarce, with second-line
chemotherapy showing only modest activity against the tumour. Despite the absence of well …

The results from the randomized phase II BELOB trial provided evidence for a potential
benefit of bevacizumab (beva), a humanized monoclonal antibody against circulating VEGF-A, …

BACKGROUND AND PURPOSE: Recovery of oculomotor (cranial nerve [CN] III) palsy after
surgery of posterior communicating artery (PcomA) aneurysms has been well documented, …

Background The BELOB study, a randomised controlled phase 2 trial comparing lomustine,
bevacizumab and combined lomustine and bevacizumab in patients with recurrent …

Leptomeningeal involvement in patients with CLL is relatively rare and the prognosis is usually
considered to be poor. The authors reviewed all CLL patients treated in a tertiary referral …

Purpose Progressive disease in patients with high-grade glioma may be reflected in cognitive
decline. However, the cognitive functions most sensitive to progression may differ between …

A woman developed a cerebellar hemangioblastoma in 1991 at the age of 17 and von
Hippel-Lindau disease was diagnosed. She underwent five craniotomies for recurrent …

… Here, we show that MCJ acts a negative regulator of mitochondrial respiration in CD8+ T
cells. MCJ deficiency did not affect proliferation of naive CD8+ T cells upon activation, nor acti…

Background The Dutch Society for Neuro-Oncology (LWNO) in collaboration with the patients’
association, developed quality criteria for glioma care. The criteria encompass the phases …

Active control of sound and vibration is a relatively new and fast growing field of research
and application. The numbers of papers published on the subject have been more than …