How reliable is perfusion MR in acute stroke? Validation and determination of the penumbra threshold against quantitative PET

M Takasawa, PS Jones, JV Guadagno, S Christensen… - Stroke, 2008 - Am Heart Assoc
Background and Purpose— Perfusion magnetic resonance imaging (pMR) is increasingly
used in acute stroke, but its physiologic significance is still debated. A reasonably good …

Applications of nitroimidazole in vivo hypoxia imaging in ischemic stroke

M Takasawa, RR Moustafa, JC Baron - Stroke, 2008 - Am Heart Assoc
Background and Purpose— Nitroimidazole imaging is a promising contender for noninvasive
in vivo mapping of brain hypoxia after stroke. However, there is a dearth of knowledge …

Prognostic value of subacute crossed cerebellar diaschisis: single-photon emission CT study in patients with middle cerebral artery territory infarct

M Takasawa, M Watanabe… - American Journal …, 2002 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Although chronic-stage crossed cerebellar diaschisis (CCD)
is reported to be associated with the neurologic state or clinical improvement after infarct, …

Association of plasma homocysteine concentration with atherosclerotic carotid plaques and lacunar infarction

T Sasaki, M Watanabe, Y Nagai, T Hoshi, M Takasawa… - Stroke, 2002 - Am Heart Assoc
Background and Purpose— Higher plasma total homocysteine (tHcy) levels have been
associated with carotid atherosclerosis and cerebral infarction in whites. However, data …

Imaging of Brain Hypoxia in Permanent and Temporary Middle Cerebral Artery Occlusion in the Rat using 18F-Fluoromisonidazole and Positron Emission …

M Takasawa, JS Beech, TD Fryer… - Journal of Cerebral …, 2007 - journals.sagepub.com
In acute stroke, the target of therapy is the severely hypoxic but salvageable tissue. Previous
human studies using 18 F-fluoromisonidazole and positron emission tomography ( 18 F-…

Neural mechanism of residual inhibition of tinnitus in cochlear implant users

Y Osaki, H Nishimura, M Takasawa, M Imaizumi… - …, 2005 - journals.lww.com
Residual inhibition is a transient suppression of tinnitus after auditory stimulation has
stopped. We used positron emission tomography to study brain regions underlying residual …

Differential brain processing of audiovisual sexual stimuli in men: comparative positron emission tomography study of the initiation and maintenance of penile erection …

…, S Takada, K Matsumiya, Y Osaki, M Takasawa… - Neuroimage, 2007 - Elsevier
The human male psychosexual cycle consists of four phases: excitation, plateau, orgasm,
and resolution. Identification of the specific neural substrates of each phase may provide …

Cerebral hemodynamics and metabolism in adult moyamoya disease: comparison of angiographic collateral circulation

…, K Matsushita, T Yoshikawa, M Takasawa… - Annals of nuclear …, 2004 - Springer
Purpose The extent of the hemodynamic and metabolic impairments in adult patients with
moyamoya disease is still controversial. The aim of the present study was to evaluate the …

Heterogeneity of cerebral blood flow in Alzheimer disease and vascular dementia

…, N Oku, M Imaizumi, M Takasawa… - American journal …, 2003 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Alzheimer disease (AD) and vascular dementia (VaD) are
the two major diseases that cause dementia, and early diagnosis is important. Single …

Statistical image analysis of cerebral blood flow in vascular dementia with small-vessel disease

…, K Kitagawa, M Imaizumi, M Takasawa… - Journal of Nuclear …, 2003 - Soc Nuclear Med
Small-vessel disease with dementia, which is the most frequent type of vascular dementia (VaD),
often shows a cerebral blood flow (CBF) distribution with no obvious focal …