The influence of sex and the presence of giant cells on postoperative long-term survival in adult patients with supratentorial glioblastoma multiforme

N Shinojima, M Kochi, JI Hamada, H Nakamura… - Journal of …, 2004 - thejns.org
Object. Glioblastoma multiforme (GBM) remains incurable by conventional treatments,
although some patients experience long-term survival. A younger age, a higher Karnofsky …

Usefulness of diffusion‐weighted MRI with echo‐planar technique in the evaluation of cellularity in gliomas

T Sugahara, Y Korogi, M Kochi… - Journal of Magnetic …, 1999 - Wiley Online Library
The purpose of this study was to evaluate the utility of diffusion‐weighted magnetic resonance
imaging (MRI) with echo‐planar imaging (EPI) technique in depicting the tumor cellularity …

Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme

N Shinojima, K Tada, S Shiraishi, T Kamiryo, M Kochi… - Cancer research, 2003 - AACR
Glioblastoma multiforme (GBM) frequently involves amplification and alteration of the
epidermal growth factor receptor (EGFR) gene, resulting in overexpression of varied mutations, …

Diffusion-weighted imaging of radiation-induced brain injury for differentiation from tumor recurrence

…, T Hirai, Y Baba, K Makino, M Kochi… - American Journal …, 2005 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Differentiation between tumor recurrence and treatment-related
brain injury is often difficult with conventional MRI. We hypothesized that the diffusion-…

Incidence and clinical features of asymptomatic meningiomas

J Kuratsu, M Kochi, Y Ushio - Journal of neurosurgery, 2000 - thejns.org
Object. The increased use of computerized tomography (CT) and magnetic resonance (MR)
technology has led to an increase in the detection of asymptomatic meningiomas, although …

Perfusion-sensitive MR imaging of gliomas: comparison between gradient-echo and spin-echo echo-planar imaging techniques

T Sugahara, Y Korogi, M Kochi… - American Journal of …, 2001 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The different sensitivities to vessel size of gradient-echo
echo-planar imaging (GE-EPI) and spin-echo EPI (SE-EPI) might indicate the relative cerebral …

Influence of p53 mutations on prognosis of patients with glioblastoma

…, H Nakamura, K Makino, M Kochi… - … Journal of the …, 2002 - Wiley Online Library
BACKGROUND The influence of p53 mutations on the biology of astrocytic tumors is
controversial. p53 is thought to be inactivated in the early stage of gliomagenesis; however, what …

Highly efficient electro-gene therapy of solid tumor by using an expression plasmid for the herpes simplex virus thymidine kinase gene

…, SB Dev, H Takeshima, M Kochi… - Proceedings of the …, 2000 - National Acad Sciences
We report successful electro-gene therapy (EGT) by using plasmid DNA for tumor-bearing
mice. Subcutaneously inoculated CT26 tumor was subjected to EGT, which consists of …

Effect of surgical removal on survival and quality of life in patients with supratentorial glioblastoma

Y Ushio, M Kochi, J Hamada, Y Kai… - Neurologia medico …, 2005 - jstage.jst.go.jp
The relationship between the extent of tumor resection and the progression-free survival,
overall survival, and quality of life was evaluated retrospectively in 105 consecutive adult …

A novel human nucleoside diphosphate (NDP) kinase, Nm23‐H6, localizes in mitochondria and affects cytokinesis

…, T Fujiwara, M Inagaki, M Kochi… - Journal of cellular …, 2000 - Wiley Online Library
Nucleoside diphosphate kinases (NDP kinases) are enzymes known to be conserved throughout
evolution and have been shown to be involved in various biological events, in addition …