We investigated the possibility that neuronal cells given a mild ischemic treatment sufficient
to perturb the cellular metabolism acquired tolerance to a subsequent, and what would be …

Background: The global ROCKET AF study evaluated once-daily rivaroxaban vs. warfarin for
stroke and systemic embolism prevention in patients with atrial fibrillation (AF). A separate …

We investigated the effects of mild and non-lethal ischemic insult on neuronal death
following subsequent lethal ischemic stress in various brain regions, using a gerbil model of …

Background and Purpose— Recently, there has been great interest in adult neurogenesis.
We investigated whether transient forebrain ischemia could influence the proliferation of …

Exposure of proteins to reducing sugars results in nonenzymatic glycation with the ultimate
formation of advanced glycation end products (AGEs). One means through which AGEs …

OBJECTIVE To quantitatively assess atherosclerosis of the carotid artery in subjects with
and without diabetes. RESEARCH DESIGN AND METHODS Ultrasound high resolution B-…

Background—An elevated plasma concentration of high-sensitivity C-reactive protein (hs-CRP)
is a strong predictor of cardiovascular events. However, there have been no longitudinal …

Background and Purpose To clarify the clinical significance of carotid atherosclerosis for
ischemic stroke events, a follow-up study was performed in Japanese patients. Methods Two …

Background and Purpose—The purpose of this study was (1) to examine the contribution of
microglia and macrophages with their interleukin-1β production and (2) to assess the …

Background and Purpose— Although the efficacy of anticoagulant therapy for primary
prevention of stroke in patients with nonvalvular atrial fibrillation (NVAF) has been established, …