MRI‐derived brain measures offer a link between genes, the environment and behavior and
have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of …

Background Bifidobacterium and Lactobacillus in the gut have been suggested to have a
beneficial effect on stress response and depressive disorder. We examined whether these …

The corpus callosum is the major commissure connecting the cerebral hemispheres, and
there is evidence of its change with aging. The sub-regions of the corpus callosum (genu, …

Clinical and animal studies suggested that a medium-chain triglyceride (MCT)-based ketogenic
diet provides an alternative energy substrate to the brain and has neuroprotective effects…

BACKGROUND: Peripheral benzodiazepine receptor (PBR) in the brain of Alzheimer's
disease (AD) patients has been discussed in relation to the role of gliosis in AD. The PBR was …

Elevated peripheral levels of interleukin-6 (IL-6) are common findings in schizophrenia and
depression. However, previous studies that measured cerebrospinal fluid (CSF) IL-6 levels …

Importance Proton magnetic resonance spectroscopy (1H-MRS) studies indicate that altered
brain glutamatergic function may be associated with the pathophysiology of schizophrenia …

This randomized, placebo-controlled, crossover, and double-blind trial aimed to examine
the possible effects of four weeks L-theanine administration on stress-related symptoms and …

Subjects with mild cognitive impairment (MCI) have “prodromal or incipient” dementia with
neuropathological changes. Peripheral benzodiazepine receptor (PBR) binding was shown to …

Objectivel-theanine, an amino acid uniquely contained in green tea (Camellia sinensis), has
been suggested to have various psychotropic effects. This study aimed to examine whether l…