BACKGROUND AND PURPOSE: Although the central processing of somatic pain has been
dealt with in numerous brain imaging studies, the neural correlates of visceral pain have …

OBJECTIVES: In healthy subjects, the neural correlates of visceral pain bear much similarity
with the correlates of somatic pain. In patients with irritable bowel syndrome, the central …

The application of functional imaging to study visceral sensation has generated
considerable interest regarding insight into the function of the brain-gut axis. Brain activation …

Visceral and somatic pain perception differs in several aspects: poor localization of visceral
pain and the ability of visceral pain to be referred to somatic structures. The perception of …

Investigation of human ano-rectal physiology has concentrated largely on understanding the
motor control of defecation and continence mechanisms. However, little is known of the …

OBJECTIVE: We sought to identify central loci that activate in response to visceral stimuli
(stool and pain). We had a particular interest in observing the anterior cingulate gyrus and …

BACKGROUND & AIMS: To characterize the cerebral processing of noxious visceral events,
changes in regional cerebral blood flow associated with perception of intestinal pain were …

Visceral pain processing is abnormal in a majority of irritable bowel syndrome (IBS) patients.
Aberrant endogenous nociceptive modulation and anticipation are possible underlying …

OBJECTIVE. Current models propose that the experience of pain includes both sensory and
affective components. Our purpose was to use functional MR imaging to determine areas of …

During the last decades there has been a tremendous development of non-invasive
methods for assessment of brain activity following visceral pain. Improved methods for …