BACKGROUND AND PURPOSE: Parkinson disease is related to neurodegeneration and
iron deposition in the substantia nigra pars compacta and nigrosome 1. However …

Background Visualisation of nigrosome 1, a substructure of the healthy substantia nigra, was
restricted in susceptibility weighted MR imaging in almost all patients with Parkinson's …

A pathological study by Damier et al demonstrated that nigrosome 1, a dopaminergic neuron-
rich region in the substantial nigra, is the most severely affected region in idiopathic …

Purpose To enhance the visibility of nigrosome 1 in substantia nigra, which has recently
been suggested as an imaging biomarker for Parkinson's disease (PD) at 3T magnetic …

Parkinson's disease (PD) is a clinically heterogeneous chronic progressive neuro-
degenerative disease with loss of dopaminergic neurons in the nigrosome 1 (N1) territory of …

Objective To determine the diagnostic characteristics of poor visualisation of nigrosome-1 as
a neuroimaging biomarker in Parkinson's disease (PD) and to explore the relationship of …

Purpose The use of susceptibility weighted imaging in high field magnetic resonance
imaging scanners can detect the nigrosome-1 area located in the caudo-lateral region of the …

Background: Brain magnetic resonance imaging (MRI) of Parkinson's disease (PD) is
performed to exclude the diagnosis of other parkinsonism diseases. In recent years, using …

Objective: This study assessed whether high-resolution 7 T MRI allowed direct in vivo
visualization of nigrosomes, substructures of the substantia nigra pars compacta (SNpc) …

Introduction Parkinson's disease (PD) is the second most common neurodegenerative
disease. However, the rate of misdiagnosis remains high, even at specialized movement …