Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial

…, S Van Gaal, A Moussaddy, D Chakraborty, N Maraj… - The Lancet, 2020 - thelancet.com
… Between March 1, 2017, and Aug 12, 2019, 1105 patients were randomly assigned to
receive nerinetide (n=549) or placebo (n=556). 337 (61·4%) of 549 patients with nerinetide and …

Letting go: Mindfulness and negative automatic thinking

PA Frewen, EM Evans, N Maraj, DJA Dozois… - Cognitive therapy and …, 2008 - Springer
Cognitive theorists describe mindfulness as a form of attention-awareness in which thoughts
can be observed in non-judging, de-centered, and non-attached ways. However, empirical …

Automated ASPECTS on noncontrast CT scans in patients with acute ischemic stroke using machine learning

…, M Najm, D Chakraborty, N Maraj… - American journal …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Alberta Stroke Program Early CT Score (ASPECTS) was
devised as a systematic method to assess the extent of early ischemic change on noncontrast …

Building the foundations for sustainable development: a case for global investment in the capabilities of adolescents

…, K Stenberg, S Chalasani, N Maharaj, N Reavley… - The Lancet, 2017 - thelancet.com
Investment in the capabilities of the world's 1·2 billion adolescents is vital to the UN's
Sustainable Development Agenda. We examined investments in countries of low income, lower-…

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein

…, RA Albrecht, MK Wang, NP Maharaj… - PLoS …, 2012 - journals.plos.org
… RIG-I is composed of two N-terminal caspase recruitment domains (CARDs), a central
DExD/H box helicase/ATPase, and a C-terminal regulatory domain (CTD/RD). Under normal …

[PDF][PDF] Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling

E Wies, MK Wang, NP Maharaj, K Chen, S Zhou… - Immunity, 2013 - cell.com
… sought to identify posttranslational modifications of the N-terminal 2CARD of MDA5 by using
… Taken together, these results indicate that MDA5 undergoes robust phosphorylation in its N-…

Assessment of discrepancies between follow-up infarct volume and 90-day outcomes among patients with ischemic stroke who received endovascular therapy

…, A Moussaddy, D Chakraborty, N Maraj… - JAMA network …, 2021 - jamanetwork.com
Importance Some patients have poor outcomes despite small infarcts after endovascular
therapy (EVT), while others with large infarcts do well. Understanding why these discrepancies …

Placental exosomes and pre-eclampsia: maternal circulating levels in normal pregnancies and, early and late onset pre-eclamptic pregnancies

P Pillay, N Maharaj, J Moodley, I Mackraj - Placenta, 2016 - Elsevier
… + exosomes compared to N (≥34 weeks) and early onset-PE groups (∼50% vs N ≥ 34 …
the late onset-PE group in comparison to N (≤33 weeks) and N (≥34 weeks) respectively. The …

Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial

…, M Boyko, MA Almekhlafi, N Newcommon, N Maraj… - The Lancet, 2024 - thelancet.com
Background Individuals with minor ischaemic stroke and intracranial occlusion are at
increased risk of poor outcomes. Intravenous thrombolysis with tenecteplase might improve …

Using field notes to facilitate critical reflection

N Maharaj - Reflective Practice, 2016 - Taylor & Francis
Taking field notes is an integral part of documentation and analysis in qualitative research.
In this paper, the author describes how field notes can be used to facilitate critical reflection …