The highly complex structure of the human brain is strongly shaped by genetic influences 1 .
Subcortical brain regions form circuits with cortical areas to coordinate movement 2 , …

Identifying genetic variants influencing human brain structures may reveal new biological
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …

Objective MRI at 3 T is said to be more accurate than 1.5 T MR, but costs and other practical
differences mean that it is unclear which to use. Methods We systematically reviewed …

General intelligence is a robust predictor of important life outcomes, including educational
and occupational attainment, successfully managing everyday life situations, good health and …

White matter hyperintensities (WMH) of presumed vascular origin are a common finding in
brain magnetic resonance imaging of older individuals and contribute to cognitive and …

The hippocampal formation is a brain structure integrally involved in episodic memory, spatial
navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal …

… NA Royle: imaging data analysis and revising the manuscript. JM Starr: study concept
and revising the manuscript. IJ Deary: study concept, interpretation of data, and revising the …

Intracranial volume reflects the maximally attained brain size during development, and remains
stable with loss of tissue in late life. It is highly heritable, but the underlying genes remain …

Rationale As the population of the world ages, age-related cognitive decline is becoming an
ever-increasing problem. However, the changes in brain structure that accompany normal …

The two hemispheres of the human brain differ functionally and structurally. Despite over a
century of research, the extent to which brain asymmetry is influenced by sex, handedness, …