Background CT perfusion (CTP) and diffusion or perfusion MRI might assist patient selection
for endovascular thrombectomy. We aimed to establish whether imaging assessments of …

Atherosclerosis leading to stenosis of the internal carotid artery is the underlying cause of 8–15%
of ischaemic strokes (symptomatic carotid stenosis). 1–2% of the adult population have …

Background Among patients with acute ischemic stroke due to occlusions in the proximal
anterior intracranial circulation, less than 40% regain functional independence when treated …

Limited data exist on clot composition and detailed characteristics of arterial thrombi
associated with large vessel occlusion in acute ischemic stroke. Advances in endovascular …

Background and Purpose—Malignant, space-occupying supratentorial ischemic stroke is
characterized by a mortality rate of up to 80%. Several reports indicate a beneficial effect of …

Background The SPACE trial is a multinational, prospective, randomised study to test the
hypothesis that carotid artery stenting is not inferior to carotid endarterectomy for treating …

Endovascular therapy (EVT) for acute ischemic stroke in selected patients has recently been
proven effective in several clinical trials, and the widespread adoption of thrombectomy into …

Background and Purpose— Diffusion-weighted MRI (DWI) has become a commonly used
imaging modality in stroke centers. The value of this method as a routine procedure is still …

Background Whether thrombectomy alone is equally as effective as intravenous alteplase
plus thrombectomy remains controversial. We aimed to determine whether thrombectomy …

Clinical observations and animal studies have raised the hypothesis that increased concentrations
of manganese (Mn) in whole blood might lead to accumulation of this metal within the …