Basic mechanisms of generalized absence seizures

OC Snead III - Annals of Neurology: Official Journal of the …, 1995 - Wiley Online Library
Snead OC. The y-hydroxybutyrate model of generalized absence seizures: further
characterization and comparison to other absence models. Epilepsia 1988;29:301-368 Vergnes M. …

[PDF][PDF] GABA, gamma-hydroxybutyric acid, and neurological disease

CGT Wong, T Bottiglieri, OC Snead - Annals of neurology, 2003 - researchgate.net
Snead OC. Antiabsence seizure activity of specific GABAB and … Snead OC. The γ-hydroxybutyrate
model of absence seizures: … Snead OC. Evidence for a G protein-coupled gamma…

γ-Hydroxybutyric acid

OC Snead III, KM Gibson - New England Journal of Medicine, 2005 - Mass Medical Soc
The short-chain fatty acid γ-hydroxybutyric acid (GHB), which is synthesized as an analogue
of γ-aminobutyric acid (GABA) that would cross the blood–brain barrier, has found limited …

ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: Position statement by the ILAE Task Force on Nosology and Definitions

…, P Samia, E Hirsch, S Galicchio, C Triki, OC Snead… - …, 2022 - Wiley Online Library
The International League Against Epilepsy (ILAE) Task Force on Nosology and Definitions
proposes a classification and definition of epilepsy syndromes in the neonate and infant with …

Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy

…, L Jardim, P Satishchandra, E Andermann, OC Snead… - Nature …, 1998 - nature.com
Lafora's disease (LD; OMIM 254780) is an autosomal recessive form of progressive myoclonus
epilepsy characterized by seizures and cumulative neurological deterioration. Onset …

[HTML][HTML] Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test

…, E Silverman, K Siriwardena, OC Snead… - Genetics in …, 2018 - nature.com
Purpose Genetic testing is an integral diagnostic component of pediatric medicine. Standard
of care is often a time-consuming stepwise approach involving chromosomal microarray …

Practice parameter: medical treatment of infantile spasms: report of the American Academy of Neurology and the Child Neurology Society

…, WD Shields, S Shinnar, E Wyllie, OC Snead III - Neurology, 2004 - AAN Enterprises
Objective: To determine the current best practice for treatment of infantile spasms in children.
Methods: Database searches of MEDLINE from 1966 and EMBASE from 1980 and …

[BOOK][B] What It Means to Be Human

OC Snead - 2020 - books.google.com
… Carter Snead proposes a framework for public bioethics rooted in a vision of human identity
… Avoiding typical dichotomies of conservative-liberal and secular-religious, Snead recasts …

High-dose corticotropin (ACTH) versus prednisone for infantile spasms: a prospective, randomized, blinded study

TZ Baram, WC Mitchell, A Tournay, OC Snead III… - …, 1996 - publications.aap.org
Objective. To compare the efficacy of corticotropin (ACTH) (150 U/m 2 /day) and prednisone
(2 mg/kg/day), given for 2 weeks, in suppressing clinical spasms and hypsarrhythmic …

Exacerbation of seizures in children by carbamazepine

OC Snead III, LC Hosey - New England Journal of Medicine, 1985 - Mass Medical Soc
We studied 15 children with complex partial seizures in whom one or more seizure type was
exacerbated during treatment with carbamazepine. The most common seizure type that was …