Cognitive impairment occurs in 40-65% of multiple sclerosis (MS) patients, typically
involving complex attention, information processing speed,(episodic) memory and executive …

Multiple sclerosis (MS) has a profound impact on health-related quality of life (HRQoL), a
comprehensive subjective measure of the patient’s health status. Assessment of HRQoL …

We investigated various magnetic resonance MRI parameters for both brain and spinal cord
to see if any improved the clinicoradiological correlation in multiple sclerosis. Ninety-one …

In six families with hereditary neuropathy with liability to pressure palsies (HNPP) the 17p11.2
deletion was absent, but single strand conformation-analysis and subsequent sequencing …

Brody's disease, ie, sarcoplasmic reticulum (SR) Ca(2+)-dependent Mg(2+)-ATPase (Ca(2+)-ATPase)
deficiency, is a rare inherited disorder of skeletal muscle function. Pseudo-…

Background Interferon beta is commonly used to treat patients with relapsing-remitting
multiple sclerosis; however, the treatment is only partially effective in reducing relapses and …

… Peter Joseph Jongen is neurologist and founding director of the MS4 Research Institute,
Nijmegen, the Netherlands. He has been involved in MS clinical research and patient care for …

Background Multiple Sclerosis (MS) is the most common cause of neurological disability in
young and middle-aged adults. At this stage in life most people are in the midst of their …

In a prospective multi-center observational study, we evaluated the frequency, severity, and
impact on activities of daily living (ADL) of adverse effects (AEs) of high-dose intravenous …

… Jongen received honoraria from Bayer for educational or consultancy activities and from
MS sherpa BV for consultancy activities. The other authors declare no conflicts of interest. …