The NINCDS–ADRDA and the DSM-IV-TR criteria for Alzheimer's disease (AD) are the
prevailing diagnostic standards in research; however, they have now fallen behind the …

In 2011, the National Institute on Aging and Alzheimer's Association created separate diagnostic
recommendations for the preclinical, mild cognitive impairment, and dementia stages of …

There is increasing evidence that subjective cognitive decline (SCD) in individuals with
unimpaired performance on cognitive tests may represent the first symptomatic manifestation of …

In the past 8 years, both the International Working Group (IWG) and the US National Institute
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …

Magnetic resonance imaging (MRI) has shown a great reduction in medial temporal lobe
and hippocampal volume of patients with Alzheimer's disease as compared to controls. …

Alzheimer's disease (AD) is classically defined as a dual clinicopathological entity. The recent
advances in use of reliable biomarkers of AD that provide in-vivo evidence of the disease …

Mild cognitive impairment is a syndrome defined as cognitive decline greater than expected
for an individual's age and education level but that does not interfere notably with activities …

… CSF tau, both total tau and phosphorylated tau (p-tau); decreased 18 fluorodeoxyglucose
(FDG) … Total tau and p-tau are treated equivalently in this study, although p-tau may have more …

Structural imaging based on magnetic resonance is an integral part of the clinical assessment
of patients with suspected Alzheimer dementia. Prospective data on the natural history of …

In this Seminar, we highlight the main developments in the field of Alzheimer's disease. The
most recent data indicate that, by 2050, the prevalence of dementia will double in Europe …