Cardiovascular safety of MnDPDP and MnCl2

P Jynge, H Brurok, A Asplund, R Towart… - Acta …, 1997 - Taylor & Francis
… Experience from ex vivo and in vivo animal experiments, p. 83. In: New developments in con…
KSENDAL AN & JYNGE P.: Myocardial protection by micromolar manganese in the calcium …

[HTML][HTML] Calmangafodipir [Ca4Mn (DPDP) 5], mangafodipir (MnDPDP) and MnPLED with special reference to their SOD mimetic and therapeutic properties

JOG Karlsson, LJ Ignarro, I Lundström, P Jynge… - Drug Discovery …, 2015 - Elsevier
… Per Jynge is a co-founder of PledPharma and owns shares in this company. PJ is inventor
on several granted patent families covering the therapeutic use of PLED derivatives. Torsten …

High performance liquid chromatography: a rapid isocratic method for determination of creatine compounds and adenine nucleotides in myocardial tissue

OFM Sellevold, P Jynge, K Aarstad - Journal of molecular and cellular …, 1986 - Elsevier
Previous methods for high performance liquid chromatography (HPLC) measurements of
myocardial high energy phosphate (HEP) compounds have used either two different assays or …

Cold cardioplegia or continuous coronary perfusion?: Report on preliminary clinical experience as assessed cytochemically

…, J Chayen, L Bitensky, DJ Hearse, P Jynge… - The Journal of thoracic …, 1977 - Elsevier
Myocardial preservation by continuous coronary perfusion is compared with cold cardioplegia.
The I L. of St. Thomas’ cardioplegic protective solution used for infusion into the coronary …

MnDPDP: Contrast agent for imaging and protection of viable tissue

P Jynge, AM Skjold, U Falkmer… - Contrast Media & …, 2020 - Wiley Online Library
… Data are expressed as mean with p values (two-tailed) included. Data in three rows to the
right were obtained by the use of late Gd-enhancement MRI (gadopentetate dimeglumine). …

The St. Thomas' hospital cardioplegic solution: a characterization in two species.

P Jynge, DJ Hearse, D Feuvray, W Mahalu… - … journal of thoracic …, 1981 - europepmc.org
Following detailed investigation and definition of some of the critical factors relating to the
composition and use of cardioplegic protective solutions, we have formulated the St. Thomas' …

Manganese Dipyridoxyl Diphosphate: MRI Contrast Agent with Antioxidative and Cardioprotective Properties?: In Vitroandex VivoAssessments

…, K Berg, JOG Karlsson, I Laursen, P Jynge - Biochemical and …, 1999 - Elsevier
Manganese dipyridoxyl diphosphate (MnDPDP) is a contrast agent for magnetic resonance
imaging (MRI) of the liver. Aims of the study were to examine if MnDPDP possesses …

Oxidative stress and inflammatory response during and following coronary interventions for acute myocardial infarction

K Berg, P Jynge, K Bjerve, S Skarra, S Basu… - Free radical …, 2005 - Taylor & Francis
… The number above the upper whiskers illustrates the p-value between 8-iso-PGF2a at the
actual time points compared to before reperfusion (t0) estimated by Wilcoxon signed ranks test…

Manganese dipyridoxyl‐diphosphate (MnDPDP) as a viability marker in patients with myocardial infarction

…, O Haraldseth, HBW Larsson, P Jynge - Journal of Magnetic …, 2007 - Wiley Online Library
… Mean precontrast R 1 was 0.87 ± 0.06 second –1 in infarcted regions and 0.96 ± 0.03 second
–1 in remote regions (P < 0.001). Mean R 1 change over one hour was 0.24 ± 0.07 second …

Myocardial protection during ischemic cardiac arrest: a possible hazard with calcium-free cardioplegic infusates

P Jynge, DJ Hearse, MV Braimbridge - The Journal of thoracic and …, 1977 - Elsevier
A number of cardioplegic and protective solutions have been described for the reduction of
cellular damage during ischemic cardiac arrest. These solutions are designed to induce …