MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image
interpretation and application of MRI diagnostic criteria contribute to misdiagnosis. Some …

Pathological evaluation is the gold standard for identifying processes related to multiple
sclerosis that explain disease manifestations, and for guiding the development of new treatments…

MRI red flags proposed over a decade ago by the European Magnetic Resonance Network
in MS (MAGNIMS) have guided clinicians in the diagnosis of multiple sclerosis (MS). …

… significantly older, had higher EDSS score, longer disease duration, higher white matter and
cortical lesion volume and a higher proportion of patients with at least one cortical lesion (P …

… [OR] = 0.79, p = 0.01) as the only predictor of worsening of disability (C-index = 0.69). Baseline
disease duration (OR = 1.50, p = 0.08) and average GM MTR (OR = 0.87, p = 0.03) were …

Objective: To assess the correlation between cognitive impairment and overall vs regional
CNS damage, quantified using conventional and diffusion tensor (DT) MRI tractography in …

Objectives: Involvement of selected central nervous system (CNS) regions has been associated
with depression and fatigue in MS. We assessed whether specific regional patterns of …

Background In 2016, the Magnetic Resonance Imaging in Multiple Sclerosis (MAGNIMS)
network proposed modifications to the MRI criteria to define dissemination in space (DIS) and …

… Results were supported by a sensitivity analysis using a non-parametric approach (p =
0.03) and a covariate analysis adjusted to MRI machine type used (p = 0.0198). …

… Sex did not differ significantly between HCs and MS patients (P = 0.3), whereas HCs were
significantly younger than MS patients (P = 0.02) and had more years of education (P < 0.0001…