Diffusion tensor imaging of the brain: review of clinical applications

PC Sundgren, Q Dong, D Gomez-Hassan, SK Mukherji… - Neuroradiology, 2004 - Springer
We review the theoretical background to diffusion tensor imaging (DTI) and some of its
commoner clinical applications, such as cerebral ischemia, brain maturation and traumatic brain …

Magnetic resonance spectroscopy

…, I Björkman-Burtscher, PC Sundgren - Journal of neuro …, 2005 - journals.lww.com
… van der Knaap MS, van der Grond J, van Rijen PC, et al. Age dependent changes in
localized proton and phosphorus MR spectroscopy of the brain. Radiology 1990;176:509-15. …

Intradural spinal tumors: current classification and MRI features

…, MM Thurnher, P McKeever, PC Sundgren - Neuroradiology, 2008 - Springer
The differential diagnosis of intradural spinal tumors is primarily based on location, but the
clinical presentation, age, and gender of the patient are also important factors in determining …

Elevated insular glutamate in fibromyalgia is associated with experimental pain

RE Harris, PC Sundgren, AD Craig… - … : Official Journal of …, 2009 - Wiley Online Library
Objective Central pain augmentation resulting from enhanced excitatory and/or decreased
inhibitory neurotransmission is a proposed mechanism underlying the pathophysiology of …

[HTML][HTML] Quantification of microscopic diffusion anisotropy disentangles effects of orientation dispersion from microstructure: applications in healthy volunteers and in …

…, S Lasič, D van Westen, PC Sundgren… - Neuroimage, 2015 - Elsevier
The anisotropy of water diffusion in brain tissue is affected by both disease and development.
This change can be detected using diffusion MRI and is often quantified by the fractional …

[HTML][HTML] Functional diffusion map as an early imaging biomarker for high-grade glioma: correlation with conventional radiologic response and overall survival

…, CR Meyer, TD Johnson, PC Sundgren… - Journal of clinical …, 2008 - ncbi.nlm.nih.gov
Purpose Assessment of radiologic response (RR) for brain tumors utilizes the Macdonald
criteria 8 to 10 weeks from the start of treatment. Diffusion magnetic resonance imaging (MRI) …

Pregabalin rectifies aberrant brain chemistry, connectivity, and functional response in chronic pain patients

…, L Pauer, J Kim, J Hampson, PC Sundgren… - …, 2013 - pubs.asahq.org
Background: Chronic pain remains a significant challenge for modern health care as its
pathologic mechanisms are largely unknown and preclinical animal models suffer from …

Differentiation between brain tumor recurrence and radiation injury using MR spectroscopy

P Weybright, PC Sundgren, P Maly… - American Journal of …, 2005 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of our study was to explore the feasibility and utility of 2D
chemical shift imaging (CSI) MR spectroscopy in the evaluation of new areas of contrast …

[HTML][HTML] Neurite density imaging versus imaging of microscopic anisotropy in diffusion MRI: A model comparison using spherical tensor encoding

…, J Mårtensson, D van Westen, PC Sundgren… - Neuroimage, 2017 - Elsevier
In diffusion MRI (dMRI), microscopic diffusion anisotropy can be obscured by orientation
dispersion. Separation of these properties is of high importance, since it could allow dMRI to non…

Dynamic levels of glutamate within the insula are associated with improvements in multiple pain domains in fibromyalgia

RE Harris, PC Sundgren, Y Pang, M Hsu… - … : Official Journal of …, 2008 - Wiley Online Library
Objective Fibromyalgia (FM) is a chronic widespread pain condition that is thought to arise
from augmentation of central neural activity. Glutamate (Glu) is an excitatory neurotransmitter …