Hypoglycemia was long considered to kill neurons by depriving them of glucose. We now
know that hypoglycemia kills neurons actively from without, rather than by starvation from within…

… Smith ML, Auer RN, Siesjd BK: The density and distribution of ischemic brain injury in the rat
… Kalimo H, Auer RN, Siesjd BK: The temporal evolution of hypoglycemic brain damage. HI. …

The widespread use of insulin and oral hypoglycaemic agents has increased the incidence
of hypoglycaemic brain damage due to accidental, suicidal, or homicidal overdose. …

The density and distribution of brain damage after 2–10 min of cerebral ischemia was studied
in the rat. Ischemia was produced by a combination of carotid clamping and hypotension, …

Rats were exposed to insulin-induced hypoglycemia resulting in periods of cerebral isoelectricity
ranging from 10 to 60 min. After recovery with glucose, they were allowed to wake up …

Hypoxia and ischaemia are distinctly different pathophysiological states. Ischaemia is
defined as a reduction of blood supply, while the hypoxic states involve a reduction of either …

In the course of a study on the pathogenesis of neuronal necrosis in severe hypoglycemia,
the morphological characteristics reflecting reversible and irreversible neuronal lesions were …

It has been repeatedly claimed that neuronal death in the hippocampal CA1 sector after
untreated global ischemia occurs via apoptosis. This is based largely on DNA laddering, nick …

Thirty-eight male Wistar rats were exposed to insulin-induced hypoglycemia resulting in
periods of cerebral isoelectricity ranging from 10 to 60 min. Plasma glucose levels during …

… Auer RN. The nature and timing of excitotoxic neuronal necrosis in thc cerebrai cortex,
hippocampus and thalamus due to flurothyl-induced status epilepticus. Acta Neuropathol (Berl) …