Testing stenting and flow diversion using a surgical elastase-induced complex fusiform aneurysm model

R Fahed, TE Darsaut, I Salazkin… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Rabbit elastase-induced saccular aneurysms have been
commonly used for preclinical testing of endovascular devices, including flow diverters …

Evaluation of a newly designed flow diverter for the treatment of intracranial aneurysms in an elastase-induced aneurysm model, in New Zealand white rabbits

A Simgen, D Ley, C Roth, U Yilmaz, H Körner… - Neuroradiology, 2014 - Springer
Introduction In this study, we analyzed angiographic and histologic aneurysm occlusion of a
newly designed flow-diverting device. Visibility and flexibility, as well as occlusions of side …

Testing flow diverters in giant fusiform aneurysms: a new experimental model can show leaks responsible for failures

TE Darsaut, F Bing, I Salazkin… - American journal of …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: FDs are the latest, most promising tool to treat giant and
complex aneurysms. Currently available experimental aneurysm models do not reproduce …

Flow diverters failing to occlude experimental bifurcation or curved sidewall aneurysms: an in vivo study in canines

TE Darsaut, F Bing, I Salazkin, G Gevry… - Journal of …, 2012 - thejns.org
Object Flow diverters (FDs) are increasingly used to treat complex intracranial aneurysms,
but preclinical studies that could guide clinical applications are lacking. The authors …

Flow diversion of giant curved sidewall and bifurcation experimental aneurysms with very-low-porosity devices

TE Darsaut, F Bing, A Makoyeva, G Gevry, I Salazkin… - World Neurosurgery, 2014 - Elsevier
Objective Flow diverters (FDs) are increasingly used to treat difficult intracranial aneurysms.
The objective of this study was to test whether treatment challenges posed by giant curved …

The success of flow diversion in large and giant sidewall aneurysms may depend on the size of the defect in the parent artery

JC Gentric, TE Darsaut, A Makoyeva… - American Journal …, 2014 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Flow diverters are designed to occlude aneurysms while
preserving flow to jailed arterial branches. We postulated that treatment success depended …

Compaction of flow diverters improves occlusion of experimental wide-necked aneurysms

JC Gentric, I Salazkin, G Gevry, J Raymond… - Journal of …, 2016 - jnis.bmj.com
Introduction Flow diverters (FDs) are increasingly used in the treatment of wide-necked
aneurysms. Objective To examine the hypothesis that intentional FD compaction might …

Evaluation of a second-generation self-expanding variable-porosity flow diverter in a rabbit elastase aneurysm model

CN Ionita, SK Natarajan, W Wang… - American journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The self-expanding V-POD is a second-generation flow-
diverting device with a low-porosity PTFE patch on a self-expanding microstent. The authors …

Evolution of flow-diverter endothelialization and thrombus organization in giant fusiform aneurysms after flow diversion: a histopathologic study

I Szikora, E Turányi, M Marosfoi - American journal of …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Treatment of giant fusiform aneurysms with flow diverters
has been associated with a relatively high rate of complications. Our goal was to study the …

Treatment of rabbit elastase-induced aneurysm models by flow diverters: development of quantifiable indexes of device performance using digital subtraction …

C Sadasivan, L Cesar, J Seong… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
It has been known for more than a decade that intracranial aneurysms can be successfully
treated by deploying a porous meshed tube in the parent vessel of the aneurysm. Such …