BACKGROUND AND PURPOSE: Hypophysitis is one of the well-known adverse effects of
immune checkpoint inhibitors. Immune checkpoint inhibitor–induced hypophysitis frequently …

Context Hypophysitis is a known immune-related adverse event (irAE) of immune
checkpoint inhibitors (CPIs), commonly associated with CTLA-4 inhibitors and less often with …

Immune checkpoint blockade-based immunotherapy is a new modality of cancer treatment
with a unique mechanism that has gained increased numbers of indication and is now used …

Immune checkpoint inhibitors (ICIs) can cause pituitary dysfunction due to hypophysitis. We
aimed to characterize ICI-induced hypophysitis and examine its association with overall …

Objective Immune checkpoint inhibitors can cause various immune-related adverse events
including secondary hypophysitis. We compared clinical characteristics of immunotherapy …

Autoimmune hypophysitis is an immune-related adverse event of immune checkpoint
inhibitors. In this article, we present the case of a 58-year-old female patient who presented …

Data on the diagnosis, natural course and management of immune checkpoint inhibitor (ICI)-
related hypophysitis (irH) are limited. We propose this study to validate the diagnostic …

Abstract Background Immune checkpoint inhibitors (ICIs) as a cancer immunotherapy have
emerged as a treatment for multiple advanced cancer types. Because of enhanced immune …

Background: Immune checkpoint inhibitors (ICI) are clinically active across multiple tumor
types but the associated immune-related adverse events (irAEs) lead to treatment delays or …

Background: Hypophysitis is a serious adverse event stemming from immune checkpoint
inhibitor (ICI) therapy for malignancy. This study aimed to characterize ICI-induced …