Outcome and prognostic factors following palliative craniospinal irradiation for leptomeningeal carcinomatosis

RA El Shafie, K Böhm, D Weber, K Lang… - Cancer management …, 2019 - Taylor & Francis
Background Leptomeningeal carcinomatosis (LC) is a severe complication of metastatic tumor
spread to the central nervous system. Prognosis is dismal with a median overall survival (…

Evaluation of particle radiotherapy for the re-irradiation of recurrent intracranial meningioma

RA El Shafie, M Czech, KA Kessel, D Habermehl… - Radiation …, 2018 - Springer
Background With the advance of modern irradiation techniques, the role of radiotherapy (RT)
for intracranial meningioma has increased significantly throughout the past years. Despite …

[HTML][HTML] Palliative radiotherapy for leptomeningeal carcinomatosis–analysis of outcome, prognostic factors, and symptom response

RA El Shafie, K Böhm, D Weber, K Lang… - Frontiers in …, 2019 - frontiersin.org
Introduction: The purpose of this article is to report our institution's 10-year experience on
palliative radiotherapy for the treatment of leptomeningeal carcinomatosis (LC), assessing …

Pre-operative versus post-operative radiosurgery of brain metastases—Volumetric and dosimetric impact of treatment sequence and margin concept

RA El Shafie, E Tonndorf-Martini, D Schmitt, D Weber… - Cancers, 2019 - mdpi.com
Background: Pre-operative radiosurgery (SRS) preceding the resection of brain metastases
promises to circumvent limitations of post-operative cavity SRS. It minimizes uncertainties …

Clinical outcome after particle therapy for meningiomas of the skull base: toxicity and local control in patients treated with active rasterscanning

RA El Shafie, M Czech, KA Kessel, D Habermehl… - Radiation …, 2018 - Springer
Background Meningiomas of the skull base account for 25–30% of all meningiomas. Due to
the complex structure of the cranial base and its close proximity to critical structures, surgery …

[HTML][HTML] Supportive care in radiotherapy based on a mobile app: prospective multicenter survey

RA El Shafie, D Weber, N Bougatf… - JMIR mHealth and …, 2018 - mhealth.jmir.org
Background: Consumer electronics and Web-enabled mobile devices are playing an
increasing role in patient care, and their use in the oncologic sector opens up promising …

Oligoprogressive non-small-cell lung cancer under treatment with PD-(L) 1 inhibitors

…, S Liersch, H Bischoff, M Kriegsmann, RA El Shafie… - Cancers, 2020 - mdpi.com
Oligoprogression (OPD) of non-small-cell lung cancer (NSCLC) occurs in approximately
half of patients under targeted compounds (TKI) and facilitates use of regional therapies that …

[HTML][HTML] Effect of timing, technique and molecular features on brain control with local therapies in oncogene-driven lung cancer

RA El Shafie, K Seidensaal, F Bozorgmehr, D Kazdal… - ESMO open, 2021 - Elsevier
Background The improved efficacy of tyrosine kinase inhibitors (TKI) mandates reappraisal
of local therapy (LT) for brain metastases (BM) of oncogene-driven non-small-cell lung …

[HTML][HTML] Single-isocenter volumetric modulated arc therapy vs. cyberKnife M6 for the stereotactic radiosurgery of multiple brain metastases

RA El Shafie, E Tonndorf-Martini, D Schmitt… - Frontiers in …, 2020 - frontiersin.org
Introduction: Stereotactic radiosurgery (SRS) is becoming more frequently used for patients
with multiple brain metastases (BMs). Single-isocenter volumetric modulated arc therapy (SI-…

[HTML][HTML] Stereotactic cavity irradiation or whole-brain radiotherapy following brain metastases resection—outcome, prognostic factors, and recurrence patterns

RA El Shafie, T Dresel, D Weber, D Schmitt… - Frontiers in …, 2020 - frontiersin.org
Introduction: Following the resection of brain metastases (BM), whole-brain radiotherapy (WBRT)
is a long-established standard of care. Its position was recently challenged by the less …