Preeclampsia (PE), which affects 4–8% of human pregnancies, causes significant maternal
and neonatal morbidity and mortality. Within the basal plate, placental cytotrophoblasts (…

Precise regulation of the formation, maintenance, and remodeling of the vasculature is required
for normal development, tissue response to injury, and tumor progression. How specific …

Specific short oligonucleotide sequences that enhance pre-mRNA splicing when present in
exons, termed exonic splicing enhancers (ESEs), play important roles in constitutive and …

… Random Forests (RF) classification of all samples based on methylation average beta values
… In a RF analysis that examined whether samples could be correctly classified as placenta, …

Cell fate decisions of pluripotent embryonic stem (ES) cells are dictated by activation and
repression of lineage-specific genes. Numerous signaling and transcriptional networks …

The causes of glioblastoma and other gliomas remain obscure 1 , 2 . To discover new
candidate genes influencing glioma susceptibility, we conducted a principal component–adjusted …

BACKGROUND AND PURPOSE: Differentiating tumor growth from posttreatment radiation
effect (PTRE) remains a common problem in neuro-oncology practice. To our knowledge, …

With the human genome sequence approaching completion, a major challenge is to identify
the locations and encoded protein sequences of all human genes. To address this problem …

Background Evaluation of cancer biomarkers from blood could significantly enable biomarker
assessment by providing a relatively non-invasive source of representative tumor material. …

The basal-like subtype of breast cancer has an aggressive clinical behavior compared to
that of the luminal subtype. We identified the microRNAs (miRNAs) miR-221 and miR-222 (miR-…