The anti-diabetic drug metformin is rapidly emerging as a potential anti-cancer agent.
Metformin, effective in treating type 2 diabetes and the insulin resistance syndromes, improves …

Background Trials of endovascular therapy for ischemic stroke have produced variable
results. We conducted this study to test whether more advanced imaging selection, recently …

Background Intravenous infusion of alteplase is used for thrombolysis before endovascular
thrombectomy for ischemic stroke. Tenecteplase, which is more fibrin-specific and has longer …

PURPOSE: To determine the histopathologic findings of patellar tendinosis ("jumper's knee")
demonstrated with ultrasonography (US) and magnetic resonance (MR) imaging. …

Background The benefit of combined treatment with intravenous thrombolysis before
endovascular thrombectomy in patients with acute ischaemic stroke caused by large vessel …

Background and Purpose— The purpose of this study was to analyze whether treating ruptured
intracranial aneurysms within 24 hours of subarachnoid hemorrhage improves clinical …

Importance Intravenous thrombolysis with tenecteplase improves reperfusion prior to
endovascular thrombectomy for ischemic stroke compared with alteplase. Objective To determine …

Background and Hypothesis Thrombolysis with tissue plasminogen activator is proven to
reduce disability when given within 4.5 h of ischemic stroke onset. However, tissue …

Background and Purpose— Basilar artery occlusion is associated with high risk of disability
and mortality. This study aimed to assess the prognostic value of a new radiological score: …

Background Follow-up infarct volume (FIV) has been recommended as an early indicator of
treatment efficacy in patients with acute ischemic stroke. Questions remain about the optimal …