CT-guided biopsy of focal lesions in patients with multiple myeloma may reveal new and more aggressive cytogenetic abnormalities

R Avva, RL Vanhemert, B Barlogie… - American journal …, 2001 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Cytogenetic abnormalities, especially chromosome 13
deletion, are high-risk factors for multiple myeloma. Attaining the highest detection rates of …

Multiple myeloma: clinical review and diagnostic imaging

EJC Angtuaco, ABT Fassas, R Walker, R Sethi… - Radiology, 2004 - pubs.rsna.org
Multiple myeloma (MM) is a malignant clonal neoplasm of plasma cells of B-lymphocyte
origin that commonly results in overproduction of large amounts of monoclonal …

18F-FDG PET/CT, 99mTc-MIBI, and MRI in evaluation of patients with multiple myeloma

R Fonti, B Salvatore, M Quarantelli… - Journal of Nuclear …, 2008 - Soc Nuclear Med
New imaging techniques have been introduced to assess the extent and severity of disease
in multiple myeloma (MM) patients. The aim of our study was to compare newer imaging …

Whole-body MRI versus whole-body MDCT for staging of multiple myeloma

A Baur-Melnyk, S Buhmann, C Becker… - American Journal of …, 2008 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of our study was to compare the detection rate of bone
manifestations of multiple myeloma in whole-body MRI compared with MDCT and to assess …

Detection of genomic abnormalities in multiple myeloma: the application of FISH analysis in combination with various plasma cell enrichment techniques

L Hartmann, JS Biggerstaff… - American journal of …, 2011 - academic.oup.com
Multiple myeloma (MM) is a hematopoietic neoplasm characterized by malignant plasma
cells (PCs) that accumulate in the bone marrow. A number of different genomic …

Cytogenetic abnormality in patients with multiple myeloma analyzed by fluorescent in situ hybridization

Y Hu, W Chen, S Chen, Z Huang - OncoTargets and therapy, 2016 - Taylor & Francis
Objective To analyze the fluorescent in situ hybridization (FISH) data and the association
with clinical characteristics, therapy response, and survival time in patients with multiple …

[CITATION][C] Histologic classification and staging of multiple myeloma

R Bartl - Hematological oncology, 1988 - Wiley Online Library
Why bone marrow biopsy (BMB) in multiple myeloma (MM)? With respect to the previous
presentations, is it still an up to date and adequate method? To give an answer we analysed …

[HTML][HTML] Detection of 14q32 rearrangements in multiple myeloma, using simultaneous FISH analysis combined with immunofluorescence

HMH Abaza, SR Youssef, AA Saad, GM Kamal… - … /Oncology and Stem Cell …, 2015 - Elsevier
Background 14q32 rearrangement has been identified as a recurrent hotspot of
translocations in multiple myeloma (MM). The Fluorescence Immunophenotyping and …

Biological and Prognostic Significance of Interphase Fluorescence in Situ Hybridization Detection of Chromosome 13 Abnormalities (Δ13) in Multiple Myeloma: An …

R Fonseca, D Harrington, MM Oken, GW Dewald… - Cancer Research, 2002 - AACR
Abstract Chromosome 13 abnormalities (Δ13) have been associated with an unfavorable
prognosis in patients with multiple myeloma (MM). The significance of this has been …

Clinical significance of chromosomal abnormalities detected by interphase fluorescencein situhybridization in newly diagnosed multiple myeloma patients

HU Yu, C Lei, C Sun, X She, LS Ai… - Chinese medical …, 2011 - journals.lww.com
Background Chromosome 13q14 deletion (del13q14), chromosome 1q21 gain (amp1q21)
and chromosome 17p13 deletion (del17p13) are the most frequent chromosomal …