We describe the full history and postmortem findings in one of the first identified cases of
mitochondrial encephalomyopathy with stroke-like episodes (MELAS). To clarify diagnostic …

Several studies suggest that there is a decrease in ventilation during sleep out of proportion
to the decrease in metabolic activity (6, 10, 24, 52, 54). The decrease in ventilation occurs …

To determine whether fibrillary astrocytes proliferate in response to brain injury, cells identified
as fibrillary astrocytes using immunoperoxidase technique for glial fibrillary acidic protein (…

Heavily T2-weighted high-field MR images provide a unique opportunity for the evaluation
of the extrapyramidal motor system. The images are affected by the presence of small …

Three independent autopsy samples of brains without apparent neuropathology were
studied to ascertain whether there was sexual dimorphism in the human corpus callosum (CC). …

3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase catalyzes the formation of
mevalonate, an essential precursor for isoprenoid compounds in mammalian cells. Recent …

The gross and light-microscopic findings at autopsy of 2 new cases of Hallervorden-Spatz
disease (HSD) of early onset and/or infantile neuroaxonal dystrophy (IND) are presented. …

In 5 patients with pharmacologically intractable epilepsy, biopsy of the cerebellar cortex at
the time of surface electrode implantation for therapeutic stimulation demonstrated marked …

Excess secretion of growth hormone (hGH) and prolactin by some pituitary tumors has been
associated with adenomas classified by tinctorial stains as acidophilic, mixed acidophilic-…

Background: Enterogenous cysts of the central nervous system are rare congenital tumors
with a single layer of mucin-secreting epithelial cells resembling gastrointestinal epithelium. …