Reaction time is negatively associated with Corpus callosum area in the early stages of CADASIL

S Delorme, F De Guio, S Reyes… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Reaction time was recently recognized as a marker of
subtle cognitive and behavioral alterations in the early clinical stages of CADASIL, a …

Decreased T1 contrast between gray matter and normal-appearing white matter in CADASIL

F De Guio, S Reyes, M Duering… - American Journal …, 2014 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: CADASIL is the most frequent hereditary small-vessel
disease of the brain. The clinical impact of various MR imaging markers has been …

Correlation of cognitive status, MRI‐and SPECT‐imaging in CADASIL patients

R Scheid, C Preul, T Lincke, G Matthes… - European journal of …, 2006 - Wiley Online Library
Although there is evidence for correlations between disability and magnetic resonance
imaging (MRI) total lesion volume in autosomal dominant arteriopathy with subcortical …

MRI lesion load of cerebral small vessel disease and cognitive impairment in patients with CADASIL

YZ Shi, SW Li, W Li, C Zhang, LY Guo, YZ Pan… - Frontiers in …, 2018 - frontiersin.org
Background and objective: Cerebral autosomal-dominant arteriopathy with subcortical
infarcts and leukoencephalopathy (CADASIL) is the best known and the most common …

Quantitative MRI in CADASIL: correlation with disability and cognitive performance

M Dichgans, M Filippi, R Bruning, G Iannucci… - Neurology, 1999 - AAN Enterprises
Objective: To study correlations between total lesion load on brain MRI and clinical features,
and to evaluate the influence of demographic variables on quantitative MRI variables in …

Cognitive alterations in non-demented CADASIL patients

H Taillia, H Chabriat, A Kurtz, M Verin, C Levy… - Cerebrovascular …, 1998 - karger.com
CADASIL is an inherited small-artery disease of the brain due to mutations of the Notch3
gene on chromosome 19. It is characterized by strokes, migraine with aura, and severe …

MRI correlates of cognitive decline in CADASIL: a 7-year follow-up study

MK Liem, SAJ Lesnik Oberstein, J Haan… - Neurology, 2009 - AAN Enterprises
Background: Cognitive decline is one of the clinical hallmarks of cerebral autosomal
dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a …

In vivo high-resolution 7 Tesla MRI shows early and diffuse cortical alterations in CADASIL

F De Guio, S Reyes, A Vignaud, M Duering, S Ropele… - PloS one, 2014 - journals.plos.org
Background and Purpose Recent data suggest that early symptoms may be related to cortex
alterations in CADASIL (Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts …

Relationship between changes in resting-state spontaneous brain activity and cognitive impairment in patients with CADASIL

J Su, M Wang, S Ban, L Wang, X Cheng, F Hua… - The Journal of …, 2019 - Springer
Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) mainly manifests with cognitive impairment. Cognitive …

Clinical correlates of longitudinal MRI changes in CADASIL

Y Ling, F De Guio, E Jouvent… - Journal of Cerebral …, 2019 - journals.sagepub.com
Previous studies showed that various types of cerebral lesions, as assessed on MRI, largely
contribute to the clinical severity of CADASIL. However, the clinical impact of longitudinal …