User profiles for S. Lu

Shun Lu

- Verified email at csco.org.cn - Cited by 33104

Shelly C Lu

- Verified email at cshs.org - Cited by 30921

Shemin Lu (吕社民)

- Verified email at mail.xjtu.edu.cn - Cited by 21656

Glutathione synthesis

SC Lu - Biochimica et Biophysica Acta (BBA)-General Subjects, 2013 - Elsevier
… Organic peroxides can also be reduced by GPx and GSH S-transferase. Catalase can also
reduce hydrogen peroxide but it is present only in peroxisome. This makes GSH particularly …

[HTML][HTML] Molecular immune pathogenesis and diagnosis of COVID-19

X Li, M Geng, Y Peng, L Meng, S Lu - Journal of pharmaceutical analysis, 2020 - Elsevier
… Coronavirus S protein has been reported as a significant determinant of virus entry into
host … [20] found that a critical proteolytic cleavage event occurred at SARS-CoV S protein at …

Regulation of hepatic glutathione synthesis: current concepts and controversies

SC Lu - The FASEB journal, 1999 - Wiley Online Library
… The -glutamyl linkage promotes intracellular stability and the sulfhydryl group is required
for GSH’s functions (Fig. 1). The peptide bond linking the amino-terminal glutamate and the …

[HTML][HTML] A trial of lopinavir–ritonavir in adults hospitalized with severe Covid-19

…, X Dong, Z Qu, S Lu, X Hu, S Ruan, S Luo… - New England journal …, 2020 - Mass Medical Soc
Background No therapeutics have yet been proven effective for the treatment of severe
illness caused by SARS-CoV-2. Methods We conducted a randomized, controlled, open-label …

[HTML][HTML] Clinical findings in 111 cases of influenza A (H7N9) virus infection

HN Gao, HZ Lu, B Cao, B Du, H Shang… - … England Journal of …, 2013 - Mass Medical Soc
Background During the spring of 2013, a novel avian-origin influenza A (H7N9) virus emerged
and spread among humans in China. Data were lacking on the clinical characteristics of …

Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a …

…, S Zhang, J Wang, S Zhou, S Ren, S Lu… - The lancet …, 2011 - thelancet.com
Background Activating mutations in EGFR are important markers of response to tyrosine
kinase inhibitor (TKI) therapy in non-small-cell lung cancer (NSCLC). The OPTIMAL study …

[HTML][HTML] Hepatitis B e antigen and the risk of hepatocellular carcinoma

HI Yang, SN Lu, YF Liaw, SL You, CA Sun… - … England Journal of …, 2002 - Mass Medical Soc
Background The presence of hepatitis B e antigen (HBeAg) in serum indicates active viral
replication in hepatocytes. HBeAg is thus a surrogate marker for the presence of hepatitis B …

Genome-wide detection of single-nucleotide and copy-number variations of a single human cell

C Zong, S Lu, AR Chapman, XS Xie - Science, 2012 - science.org
… Although improving the polymerase’s error rate is possible, our strategy to reduce the
false-positive rate was to sequence two or three kindred cells derived from the same cell. The …

CDD: a Conserved Domain Database for the functional annotation of proteins

A Marchler-Bauer, S Lu, JB Anderson… - Nucleic acids …, 2010 - academic.oup.com
NCBI’s Conserved Domain Database (CDD) is a resource for the annotation of protein
sequences with the location of conserved domain footprints, and functional sites inferred from …

Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral …

Y Hu, S Lu, Z Song, W Wang, P Hao, J Li, X Zhang… - The Lancet, 2013 - thelancet.com
Background On March 30, a novel influenza A subtype H7N9 virus (A/H7N9) was detected
in patients with severe respiratory disease in eastern China. Virological factors associated …