Epithelial–mesenchymal transition (EMT) encompasses dynamic changes in cellular organization
from epithelial to mesenchymal phenotypes, which leads to functional changes in cell …

… The total RNA was extracted from these infected cells and used to clone and sequence the
causative agent(s). Most of sequence reads matched against the lineage B of the genus beta-…

The epithelial-mesenchymal transition (EMT) is a key developmental program that is often
activated during cancer invasion and metastasis. We here report that the induction of an EMT …

… Mani et al. showed that induction of EMT in immortalized human mammary epithelial
cells results in de novo expression of stem-cell markers and acquisition of functional stem-cell …

Metastasis is a multistep process during which cancer cells disseminate from the site of
primary tumors and establish secondary tumors in distant organs. In a search for key regulators …

Antibodies targeting CTLA-4 have been successfully used as cancer immunotherapy. We
find that the antitumor effects of CTLA-4 blockade depend on distinct Bacteroides species. In …

Loss of the epithelial adhesion molecule E-cadherin is thought to enable metastasis by
disrupting intercellular contacts—an early step in metastatic dissemination. To further investigate …

Although progesterone has been recognized as essential for the establishment and maintenance
of pregnancy, this steroid hormone has been recently implicated to have a functional …

… We hypothesized that the physiological level of endogenous H 2 S limits the development of
… Joseph’s Healthcare Hamilton is also acknowledged. Dr Mani was supported by a research …

The dose-limiting side effect of the common colon cancer chemotherapeutic CPT-11 is severe
diarrhea caused by symbiotic bacterial β-glucuronidases that reactivate the drug in the gut…