Stem cell biology has come of age. Unequivocal proof that stem cells exist in the haematopoietic
system has given way to the prospective isolation of several tissue-specific stem and …

Phenotypic and functional heterogeneity arise among cancer cells within the same tumour
as a consequence of genetic change, environmental differences and reversible changes in …

Niches are local tissue microenvironments that maintain and regulate stem cells. Haematopoiesis
provides a model for understanding mammalian stem cells and their niches, but the …

… On the other hand, in a strictly surface site (surface molecule) model, interaction with the
bands is ignored and local interaction with the neighboring substrate atom(s) is emphasized. …

The objective of the present volume is to develop the theory and practice of nonmetal
electrochemistry from first principles, emphasizing energy level models, in particular the fluctuating …

Background: Transgender healthcare is a rapidly evolving interdisciplinary field. In the last
decade, there has been an unprecedented increase in the number and visibility of …

Breast cancer is the most common malignancy in United States women, accounting for >40,000
deaths each year. These breast tumors are comprised of phenotypically diverse …

Background Antiretroviral preexposure prophylaxis is a promising approach for preventing
human immunodeficiency virus type 1 (HIV-1) infection in heterosexual populations. Methods …

To improve our ability to identify hematopoietic stem cells (HSCs) and their localization in
vivo, we compared the gene expression profiles of highly purified HSCs and non-self-renewing …

A fundamental question in cancer biology is whether cells with tumorigenic potential are
common or rare within human cancers. Studies on diverse cancers, including melanoma, have …