Nampt: linking NAD biology, metabolism and cancer

A Garten, S Petzold, A Körner, S Imai… - Trends in endocrinology & …, 2009 - cell.com
Nicotinamide phosphoribosyltransferase (Nampt) converts nicotinamide to nicotinamide
mononucleotide (NMN), a key nicotinamide adenine dinucleotide (NAD) intermediate. …

Standardized assessment of automatic segmentation of white matter hyperintensities and results of the WMH segmentation challenge

…, BY Park, H Park, SH Park, S Pezold… - IEEE transactions on …, 2019 - ieeexplore.ieee.org
… Tests for age and volumes were performed using Welch’s unequal variances t-test [64].
Tests for gender and presence of lacunes were performed using Fisher’s exact test. …

Adipocytes and adipose tissue

W Kiess, S Petzold, M Töpfer, A Garten, S Blüher… - Best practice & research …, 2008 - Elsevier
An epidemic of obesity is taking place in most societies around the world. Overall obesity
substantially increases the risk of subsequent morbidity. In children and adolescents the …

Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine

G Sommer, A Garten, S Petzold… - Clinical …, 2008 - portlandpress.com
… toxin also caused a significant down-regulation of visfatin/PBEF/Nampt mRNA, the effect
of isoprenaline on visfatin/PBEF/Nampt synthesis is probably mediated via a classical G s -…

Multi-dimensional gated recurrent units for the segmentation of biomedical 3D-data

S Andermatt, S Pezold, P Cattin - Deep Learning and Data Labeling for …, 2016 - Springer
We present a supervised deep learning method to automatically segment 3D volumes of
biomedical image data. The presented method takes advantage of a neural network with the …

Spinal cord volume loss: a marker of disease progression in multiple sclerosis

C Tsagkas, S Magon, L Gaetano, S Pezold… - Neurology, 2018 - AAN Enterprises
Objective Cross-sectional studies have shown that spinal cord volume (SCV) loss is related
to disease severity in multiple sclerosis (MS). However, long-term data are lacking. Our aim …

Automated segmentation of multiple sclerosis lesions using multi-dimensional gated recurrent units

S Andermatt, S Pezold, PC Cattin - … 2017, Held in Conjunction with MICCAI …, 2018 - Springer
We analyze the performance of multi-dimensional gated recurrent units on automated lesion
segmentation in multiple sclerosis. The segmentation of these pathologic structures is not …

Preferential spinal cord volume loss in primary progressive multiple sclerosis

…, S Magon, L Gaetano, S Pezold… - Multiple Sclerosis …, 2019 - journals.sagepub.com
… of follow-ups between subtypes were made using Welch’s two-sample t-tests and Pearson’s
Chi-square test with Yate’s continuity correction. Between-group differences in regard to …

Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes

A Garten, S Petzold, A Barnikol-Oettler, A Körner… - Biochemical and …, 2010 - Elsevier
Circulating NAMPT (PBEF/visfatin) has pleiotropic functions and is secreted from adipocytes.
Since it is doubtful whether serum levels can be explained by secretion from adipocytes …

Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes

…, MG Levisetti, B Calderon, JW Herzog, SJ Petzold… - Nature …, 2010 - nature.com
In addition to the genetic framework, there are two other critical requirements for the
development of tissue-specific autoimmune disease. First, autoreactive T cells need to escape …