Quantitative susceptibility mapping (QSM) has enabled magnetic resonance imaging (MRI)
of tissue magnetic susceptibility to advance from simple qualitative detection of hypointense …

Magnetic resonance imaging (MRI) has developed into the most important tool for the
diagnosis and monitoring of multiple sclerosis (MS). Its high sensitivity for the evaluation of …

Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system (CNS)
resulting in various disabilities including weakness and imbalance, visual abnormalities, …

In vitro studies have shown that neuronal cell cultures secrete exosomes containing amyloid-β
precursor protein (APP) and the APP-processing products, C-terminal fragments (CTFs) …

Cognitive dysfunction is common in patients with multiple sclerosis (MS), and has been
associated with MRI measures of lesion burden and atrophy. Little is known about the …

Purpose To assess multiple sclerosis (MS) lesions at various ages by using quantitative
susceptibility mapping (QSM) and conventional magnetic resonance (MR) imaging. Materials …

Chronic active multiple sclerosis lesions, characterized by a hyperintense rim of iron-enriched,
activated microglia and macrophages, have been linked to greater tissue damage. Post-…

Neuroendocrine cells are specialized to produce, maintain and release large stores of
secretory peptides. We show that the Drosophila dimmed/Mist1 bHLH gene confers such a pro-…

A dysfunctional endosomal pathway and abnormally enlarged early endosomes in neurons
are an early characteristic of Down syndrome (DS) and Alzheimer’s disease (AD). We have …

Purpose To measure the longitudinal change in multiple sclerosis (MS) lesion susceptibility
using quantitative susceptibility mapping (QSM). Materials and Methods The study was …