Intracranial aneurysms (IAs) linger as a potentially devastating clinical problem. Despite
intense investigation, our understanding of the mechanisms leading to aneurysm development, …

Aim: The “2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid
Hemorrhage” replaces the 2012 “Guidelines for the Management of Aneurysmal …

Purpose: Central retinal artery occlusion (CRAO) is a form of acute ischemic stroke that
causes severe visual loss and is a harbinger of further cerebrovascular and cardiovascular …

Background Emergence of the novel corona virus (severe acute respiratory syndrome (SARS)-CoV-2)
in December 2019 has led to the COVID-19 pandemic. The extent of COVID-19 …

OBJECT The factors that contribute to periprocedural complications following cranioplasty,
including patient-specific and surgery-specific factors, need to be thoroughly assessed. The …

Background The coronavirus disease 2019 is associated with neurological manifestations
including stroke. Objectives We present a case series of coronavirus disease 2019 patients …

Little is known about vascular smooth muscle cell (SMC) phenotypic modulation in the
cerebral circulation or pathogenesis of intracranial aneurysms. Tumor necrosis factor-alpha (TNF-…

Cerebral cavernous malformations are the most common vascular malformations and can be
found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral …

Smoking is an established risk factor for subarachnoid hemorrhage yet the underlying
mechanisms are largely unknown. Recent data has implicated a role of inflammation in the …

Oxidative stress is known to contribute to the progression of cerebrovascular disease.
Additionally, oxidative stress may be increased by, but also augment inflammation, a key …