Cognitive aging, executive function, and fractional anisotropy: a diffusion tensor MR imaging study

SM Grieve, LM Williams, RH Paul… - American Journal of …, 2007 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Fractional anisotropy (FA) is a useful measure of
connectivity in the brain that can be derived from the diffusion tensor imaging (DTI) dataset …

Multimodal imaging in mild cognitive impairment: Metabolism, morphometry and diffusion of the temporal–parietal memory network

KB Walhovd, AM Fjell, I Amlien, R Grambaite, V Stenset… - Neuroimage, 2009 - Elsevier
This study compared sensitivity of FDG-PET, MR morphometry, and diffusion tensor imaging
(DTI) derived fractional anisotropy (FA) measures to diagnosis and memory function in mild …

Regionally-specific diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease

MM Mielke, NA Kozauer, KCG Chan, M George… - Neuroimage, 2009 - Elsevier
BACKGROUND: Diffusion tensor imaging (DTI) studies have shown significant cross-
sectional differences among normal controls (NC) mild cognitive impairment (MCI) and …

Diffusion tensor imaging and tract-based spatial statistics in Alzheimer's disease and mild cognitive impairment

Y Liu, G Spulber, KK Lehtimäki, M Könönen… - Neurobiology of …, 2011 - Elsevier
We aimed to explore the changes in fractional anisotropy (FA) in subjects with mild cognitive
impairment (MCI) and Alzheimer's disease (AD) by analyzing diffusion tensor imaging (DTI) …

White matter damage in frontotemporal dementia and Alzheimer's disease measured by diffusion MRI

Y Zhang, N Schuff, AT Du, HJ Rosen, JH Kramer… - Brain, 2009 - academic.oup.com
Frontotemporal dementia (FTD) and Alzheimer's disease are sometimes difficult to
differentiate clinically because of overlapping symptoms. Using diffusion tensor imaging …

Age‐related changes in prefrontal white matter measured by diffusion tensor imaging

DH Salat, DS Tuch, ND Hevelone… - Annals of the New …, 2005 - Wiley Online Library
Age‐related degeneration of brain white matter (WM) has received a great deal of attention,
with recent studies demonstrating that such changes are correlated with cognitive decline …

White matter damage on diffusion tensor imaging correlates with age-related cognitive decline

RA Charlton, TR Barrick, DJ McIntyre, Y Shen… - Neurology, 2006 - AAN Enterprises
Background: Damage to white matter tracts, resulting in “cerebral disconnection,” may
underlie age-related cognitive decline. Methods: Using diffusion tensor MRI (DTI) to …

Exploratory voxel-based analysis of diffusion indices and hemispheric asymmetry in normal aging

S Ardekani, A Kumar, G Bartzokis, U Sinha - Magnetic resonance imaging, 2007 - Elsevier
Age-related microstructural changes in brain white matter can be studied by utilizing indices
derived from diffusion tensor imaging (DTI): apparent diffusion coefficient (ADC) and …

The fornix sign: a potential sign for Alzheimer's disease based on diffusion tensor imaging

K Oishi, MM Mielke, M Albert… - Journal of …, 2012 - Wiley Online Library
ABSTRACT BACKGROUND We investigated a simple imaging sign for Alzheimer's disease
(AD), using diffusion tensor imaging (DTI). We hypothesized that a reduction in fractional …

Potential role of diffusion tensor MRI in the differential diagnosis of mild cognitive impairment and Alzheimer's disease

D B. Parente, EL Gasparetto… - American Journal of …, 2008 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study was to evaluate the fractional anisotropy values of
several white matter tracts with the aim of differentiating a healthy population from persons …