Tumor cell proliferation requires rapid synthesis of macromolecules including lipids, proteins,
and nucleotides. Many tumor cells exhibit rapid glucose consumption, with most of the …

In recent years, a variety of low molecular weight antibiotics have been isolated from
diverse animal species. These agents, which include peptides, lipids, and alkaloids, exhibit …

Recent evidence indicates that the type of atherosclerotic plaque, rather than the degree of
obstruction to flow, is an important determinant of the risk of cardiovascular complications. In …

Magnetic resonance imaging has previously demonstrated its potential for indirectly mapping
myelin density, either by relaxometric detection of myelin water or magnetization transfer. …

Anisotropy of water diffusion in axon tracts, as determined by diffusion-weighted MRI, has
been assumed to reflect the restriction of water diffusion across axon membranes. Reduction …

Our objective was to study brain amino acid metabolism in response to ketosis. The underlying
hypothesis is that ketosis is associated with a fundamental change of brain amino acid …

Background—The pathogenesis of atherosclerosis is currently being investigated in
genetically engineered small animals. Methods to follow the time course of the developing …

Q-space imaging (QSI), a diffusion MRI technique, can provide quantitative tissue architecture
information at cellular dimensions not amenable by conventional diffusion MRI. By …

Two major products (adducts A and B) from the reaction of 2‘-deoxyguanosine (dGuo) with
13-hydroperoxylinoleic acid were detected by liquid chromatography/mass spectrometry (LC/…

The rate-limiting step in the delivery of nutrients to osteocytes and the removal of cellular waste
products is likely diffusion. The transport of osteoid water across the mineralized matrix of …