Molecular imaging in living subjects: seeing fundamental biological processes in a new light

TF Massoud, SS Gambhir - Genes & development, 2003 - genesdev.cshlp.org
Morphological observations have driven the course of biology ever since the first microscope
was built in the late sixteenth century. Molecular imaging is a rapidly emerging biomedical …

Gold nanoparticles: a revival in precious metal administration to patients

AS Thakor, J Jokerst, C Zavaleta, TF Massoud… - Nano …, 2011 - ACS Publications
Gold has been used as a therapeutic agent to treat a wide variety of rheumatic diseases
including psoriatic arthritis, juvenile arthritis, and discoid lupus erythematosus. Although the use …

Biophysical mechanisms of stroke

GJ Hademenos, TF Massoud - Stroke, 1997 - Am Heart Assoc
Background Stroke is the third leading cause of death and the leading cause of long-term
disability in the United States. Although a host of genetic, biochemical, physiological, anatomic…

Polymer nanoparticles mediated codelivery of antimiR-10b and antimiR-21 for achieving triple negative breast cancer therapy

…, NM Sekar, TV Sekar, K Foygel, TF Massoud… - ACS …, 2015 - ACS Publications
TF Massoud, JK Willmann helped with experimental design and manuscript writing. R. …
Massoud, Ramasamy Paulmurugan. SP94-Targeted Triblock Copolymer Nanoparticle Delivers …

Correlation of the angioarchitectural features of cerebral arteriovenous malformations with clinical presentation of hemorrhage

F Turjman, TF Massoud, F Viñuela, JW Sayre… - …, 1995 - journals.lww.com
SUPERSELECTIVE ANGIOGRAPHY IS the most accurate technique in the analysis of brain
arteriovenous malformation (AVM) angioarchitecture. Therefore, we reviewed the selective …

Bioluminescence resonance energy transfer (BRET) imaging of protein–protein interactions within deep tissues of living subjects

…, CT Chan, A De, TF Massoud… - Proceedings of the …, 2011 - National Acad Sciences
Identifying protein–protein interactions (PPIs) is essential for understanding various disease
mechanisms and developing new therapeutic approaches. Current methods for assaying …

Intranasal delivery of targeted polyfunctional gold–iron oxide nanoparticles loaded with therapeutic microRNAs for combined theranostic multimodality imaging and …

…, F Habte, R Sinclair, SS Gambhir, TF Massoud… - Biomaterials, 2019 - Elsevier
The prognosis for glioblastoma (GBM) remains depressingly low. The biological barriers of
the brain present a major challenge to achieving adequate drug concentrations for GBM …

The fate and toxicity of Raman-active silica-gold nanoparticles in mice

…, P Kempen, C Zavaleta, P Chu, TF Massoud… - Science translational …, 2011 - science.org
Raman spectroscopy is an optical imaging method that is based on the Raman effect, the
inelastic scattering of a photon when energy is absorbed from light by a surface. Although …

Tumor cell-derived extracellular vesicle-coated nanocarriers: an efficient theranostic platform for the cancer-specific delivery of anti-miR-21 and imaging agents

…, SJ Pitteri, R Sinclair, JK Willmann, TF Massoud… - ACS …, 2018 - ACS Publications
MicroRNAs are critical regulators of cancer initiation, progression, and dissemination. Extensive
evidence suggests that the inhibition of over-expressed oncogenic miRNA function can …

Epilepsy associated with cerebral arteriovenous malformations: a multivariate analysis of angioarchitectural characteristics.

F Turjman, TF Massoud, JW Sayre… - American Journal …, 1995 - Am Soc Neuroradiology
PURPOSE To identify the morphological vascular characteristics of cerebral arteriovenous
malformations (AVMs) that predict a clinical presentation of epilepsy. METHOD Fifteen …