User profiles for T Sato

Tatsuhiko Sato

Japan Atomic Energy Agency
Verified email at jaea.go.jp
Cited by 8875

Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications

T Sato, H Clevers - Science, 2013 - science.org
Recent examples have highlighted how stem cells have the capability to initiate morphogenesis
in vitro; that is, to generate complex structures in culture that closely parallel their in vivo …

Global, regional, and country level need for data on wastewater generation, treatment, and use

T Sato, M Qadir, S Yamamoto, T Endo… - Agricultural Water …, 2013 - Elsevier
Irrigation with wastewater supports agricultural production and the livelihoods of millions of
smallholder farmers in many parts of the world. Considering the importance of better …

Correlated coding of motivation and outcome of decision by dopamine neurons

T Satoh, S Nakai, T Sato, M Kimura - Journal of neuroscience, 2003 - Soc Neuroscience
We recorded the activity of midbrain dopamine neurons in an instrumental conditioning task
in which monkeys made a series of behavioral decisions on the basis of distinct reward …

Structure, regulation and function of ghrelin

T Sato, Y Nakamura, Y Shiimura… - The Journal of …, 2012 - academic.oup.com
… (54) established a ghrelin-producing cell line MGN3-1 from a gastric ghrelin-producing cell
tumour derived from transgenic mice in which SV40 Large T antigen was expressed under …

Complete sequencing and characterization of 21,243 full-length human cDNAs

…, T Komatsu, J Mizushima-Sugano, T Satoh… - Nature …, 2004 - nature.com
As a base for human transcriptome and functional genomics, we created the “full-length long
Japan” (FLJ) collection of sequenced human cDNAs. We determined the entire sequence …

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

T Sato, RG Vries, HJ Snippert, M Van De Wetering… - Nature, 2009 - nature.com
The intestinal epithelium is the most rapidly self-renewing tissue in adult mammals. We have
recently demonstrated the presence of about six cycling Lgr5 + stem cells at the bottoms of …

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

T Sato, JH Van Es, HJ Snippert, DE Stange, RG Vries… - Nature, 2011 - nature.com
… l–t, Paneth cells and stem cells in inducible Paneth cell depletion model. Mice of the indicated
genotype were injected with β-napthoflavone to induce Cre and were analysed 54 or 67 …

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

TN Sato, Y Tozawa, U Deutsch, K Wolburg-Buchholz… - Nature, 1995 - nature.com
TIE-1 and Tie-2 define a new class of receptor tyrosine kinases that are specifically expressed
in developing vascular endothelial cells. To study the functions of Tie-1 and Tie-2 during …

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

…, N Papadopoulos, TJ Daly, S Davis, TN Sato… - Science, 1997 - science.org
Angiogenesis is thought to depend on a precise balance of positive and negative regulation.
Angiopoietin-1 (Ang1) is an angiogenic factor that signals through the endothelial cell–…

Features of particle and heavy ion transport code system (PHITS) version 3.02

T Sato, Y Iwamoto, S Hashimoto, T Ogawa… - Journal of Nuclear …, 2018 - Taylor & Francis
We have upgraded many features of the Particle and Heavy Ion Transport code System (PHITS)
and released the new version as PHITS3.02. The accuracy and the applicable energy …