User profiles for T. Gonen

Tamir Gonen

Professor UCLA, HHMI Investigator
Verified email at ucla.edu
Cited by 15342

The structure of aquaporins

T Gonen, T Walz - Quarterly reviews of biophysics, 2006 - cambridge.org
… protein, into artificial lipid bilayers produced large double-layered 2D crystals, which
were used to determine the structure of AQP0 by electron crystallography to 3 A resolution (Gonen

The cryo-EM method microcrystal electron diffraction (MicroED)

BL Nannenga, T Gonen - Nature methods, 2019 - nature.com
In 2013 we established a cryo-electron microscopy (cryo-EM) technique called microcrystal
electron diffraction (MicroED). Since that time, data collection and analysis schemes have …

Secretins: dynamic channels for protein transport across membranes

KV Korotkov, T Gonen, WGJ Hol - Trends in biochemical sciences, 2011 - cell.com
Secretins form megadalton bacterial-membrane channels in at least four sophisticated
multiprotein systems that are crucial for translocation of proteins and assembled fibers across the …

Lipid–protein interactions in double-layered two-dimensional AQP0 crystals

T Gonen, Y Cheng, P Sliz, Y Hiroaki, Y Fujiyoshi… - Nature, 2005 - nature.com
Lens-specific aquaporin-0 (AQP0) functions as a specific water pore and forms the thin
junctions between fibre cells. Here we describe a 1.9 Å resolution structure of junctional AQP0, …

Covid-19 breakthrough infections in vaccinated health care workers

M Bergwerk, T Gonen, Y Lustig, S Amit… - … England Journal of …, 2021 - Mass Medical Soc
Background Despite the high efficacy of the BNT162b2 messenger RNA vaccine against
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), rare breakthrough infections …

Aquaporin-0 membrane junctions reveal the structure of a closed water pore

T Gonen, P Sliz, J Kistler, Y Cheng, T Walz - Nature, 2004 - nature.com
The lens-specific water pore aquaporin-0 (AQP0) is the only aquaporin known to form
membrane junctions in vivo 1 . We show here that AQP0 from the lens core, containing some …

[BOOK][B] Electric power distribution engineering

T Gonen - 2015 - books.google.com
As attractive to students as it is useful to professors and engineers, this third edition of a
groundbreaking textbook demonstrates how to design, analyze, and perform modern distribution …

[BOOK][B] Modern power system analysis

T Gonen - 2016 - books.google.com
Gonen was professor of electrical engineering and director … Gonen also has a strong
background in the power industry; … Professor Gonen has written over 100 technical papers as well …

Efficacy of a fourth dose of Covid-19 mRNA vaccine against Omicron

G Regev-Yochay, T Gonen, M Gilboa… - … England Journal of …, 2022 - Mass Medical Soc
A Fourth Dose of mRNA Vaccine in Health Care Workers Health care workers in Israel were
given a fourth dose of BNT162b2 or mRNA-1273 vaccine during a period of omicron-variant …

Computational design of self-assembling protein nanomaterials with atomic level accuracy

…, BS Vollmar, JP Sumida, I André, T Gonen… - Science, 2012 - science.org
… (T) or octahedral (O) point group symmetry (Fig. 1). An assembly with symmetry T requires
… (29) were docked symmetrically in both the T and O target architectures by aligning the three…