… ( 24 ) Nox5 is expressed in human T and B lymphocytes of spleen and lymph nodes, ( 5 )
but its biological role, to date, remains elusive. Duox2 mediates both lactoperoxidase-…

… T-cell costimulation specific to LFA-1–ICAM-1 binding. Lovastatin and mevastatin completely
blocked the proliferative response of T … which seems to interfere with the T-cell response by …

… seems that growth factors alter the state of tyrosine phosphorylation of at least two other
membrane-associated oncogene or proto-oncogene proteins (EGF stimulated polyoma middle T …

Integrity in research is fundamental to the advancement of knowledge, for the public’s support
of research, and the autonomy of the academic profession. Misconduct in the forms of …

Exposure of platelets to shear stress leads to aggregation in the absence of exogenous
agonists. We have now found that different adhesive proteins and platelet membrane …

Background: Omeprazole is metabolized by S-mephenytoin 4′-hydroxylase (CYP2C19) in
the liver. In persons with a poor-metabolizer genotype for CYP2C19, the therapeutic efficacy …

The activated Ras oncogene can transform various mammalian cells and has been implicated
in development of a high population of malignant human tumors. Recent studies suggest …

… N: nuclear fraction, Cyt: cytosolic fraction, T: total extract using TNT buffer, Sup: supernatant
of … Fujigasaki, and T. Shiojiri for their technical advice on molecular cloning and T. Furuya for …

… The normal protein did hydrolyse GTP to GDP with an estimated t, , of -2 h (reaction 1). In
contrast, a much slower rate of hydrolysis was seen with the T24 transforming protein (reaction …

Ag (for RA measurements) and on ZnSe (for transmission measurements) substrates gave
reasonable tilt angles for the molecular chain as compared to those reported by other …