Background Endovascular therapy is increasingly used after the administration of intravenous
tissue plasminogen activator (t-PA) for patients with moderate-to-severe acute ischemic …

Methods A hybrid approach based on established processes described by Glaser15 and by
the National Institutes of Health (http://prevention. nih. gov/cdp/about. aspx) 16 was used to …

Background and Purpose—The purpose of this study was to test the feasibility, efficacy, and
safety of combined intravenous (IV) and local intra-arterial (IA) recombinant tissue …

Background: Trials of IV recombinant tissue plasminogen activator (rt-PA) have demonstrated
that longer times from ischemic stroke symptom onset to initiation of treatment are …

Background The IMS III trial did not show a clinical benefit of endovascular treatment
compared with intravenous alteplase (recombinant tissue plasminogen activator) alone for …

DIRECT CAROTID-CAVERNOUS FISTULAS are high-flow shunts with a direct connection
between the internal carotid artery and the cavernous sinus. The goals of treatment are to …

Background and Purpose— Little is known about the relationship between perihematomal
edema in spontaneous intracerebral hemorrhage (ICH) and outcome. The purpose of this …

Background and Purpose— Endovascular strategies provide unique opportunity to correlate
angiographic measures of collateral circulation at the time of endovascular therapy. We …

Background and Purpose— The natural history of perihematomal edema in human hyperacute
spontaneous intracerebral hemorrhage (ICH) has not been well described. Methods— …

Rationale The Interventional Management of Stroke (IMS) I and II pilot trials demonstrated
that the combined intravenous (iv) and intraarterial (ia) approach to recanalization may be …