Sodium MR neuroimaging

…, M Bydder, TC Oughourlian… - American Journal …, 2021 - Am Soc Neuroradiology
Sodium MR imaging has the potential to complement routine proton MR imaging examinations
with the goal of improving diagnosis, disease characterization, and clinical monitoring in …

Evolution of brain functional plasticity associated with increasing symptom severity in degenerative cervical myelopathy

C Wang, BM Ellingson, TC Oughourlian, N Salamon… - …, 2022 - thelancet.com
Background Advanced imaging modalities have helped elucidate the cerebral alterations
associated with neurological impairment caused by degenerative cervical myelopathy (DCM), …

Diffusion MRI is an early biomarker of overall survival benefit in IDH wild-type recurrent glioblastoma treated with immune checkpoint inhibitors

A Hagiwara, TC Oughourlian, NS Cho… - Neuro …, 2022 - academic.oup.com
Background Diffusion MRI estimates of the apparent diffusion coefficient (ADC) have been
shown to be useful in predicting treatment response in patients with glioblastoma (GBM), with …

Rate of change in maximum 18F-FDOPA PET uptake and non-enhancing tumor volume predict malignant transformation and overall survival in low-grade gliomas

TC Oughourlian, J Yao, J Schlossman… - Journal of neuro …, 2020 - Springer
Purpose To examine whether the rate of change in maximum 18 F-FDOPA PET uptake and
the rate of change in non-enhancing tumor volume could predict malignant transformation …

Relative oxygen extraction fraction (rOEF) MR imaging reveals higher hypoxia in human epidermal growth factor receptor (EGFR) amplified compared with non …

TC Oughourlian, J Yao, A Hagiwara, DA Nathanson… - Neuroradiology, 2021 - Springer
Purpose Epidermal growth factor receptor (EGFR) amplification promotes gliomagenesis and
is linked to lack of oxygen within the tumor microenvironment. Using hypoxia-sensitive spin…

Sex-dependent cortical volume changes in patients with degenerative cervical myelopathy

TC Oughourlian, C Wang, N Salamon, LT Holly… - Journal of clinical …, 2021 - mdpi.com
Degenerative cervical myelopathy (DCM) is a progressive condition characterized by
degeneration of osseocartilaginous structures within the cervical spine resulting in compression of …

Depth of Radiographic Response and Time to Tumor Regrowth Predicts Overall Survival Following Anti-VEGF Therapy in Recurrent Glioblastoma

…, NS Cho, S Oshima, F Sanvito, TC Oughourlian… - Clinical Cancer …, 2023 - AACR
Purpose: Antiangiogenic therapies are known to cause high radiographic response rates due
to reduction in vascular permeability resulting in a lower degree of contrast extravasation. …

Symptom-associated alterations in functional connectivity in primary and secondary provoked vestibulodynia

TC Oughourlian, G Tun, KM Antony, A Gupta, VM Mays… - Pain, 2023 - journals.lww.com
Primary provoked vestibulodynia (PVD) is marked by the onset of symptoms at first provoking
vulvar contact, whereas secondary PVD refers to symptom onset after some period of …

Voxelwise and patientwise correlation of 18F-FDOPA PET, relative cerebral blood volume, and apparent diffusion coefficient in treatment-naïve diffuse gliomas with …

…, A Hagiwara, J Yao, TC Oughourlian… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Our purpose was to identify correlations between 18 F-fluorodihydroxyphenylalanine ( 18 F-FDOPA)
uptake and physiologic MRI, including relative cerebral blood volume (rCBV) and …

Diagnostic and prognostic value of pH-and oxygen-sensitive magnetic resonance imaging in glioma: a retrospective study

J Yao, A Hagiwara, TC Oughourlian, C Wang… - Cancers, 2022 - mdpi.com
Simple Summary Gliomas are known to present with an altered metabolic phenotype that
contributes to the abnormal tumor microenvironment detectable on MRI. The aim of this study …