Intrathecal urokinase infusion through a microcatheter into the cisterna magna to prevent cerebral vasospasm: experimental study in dogs

T Mizuno, J Hamada, Y Kai, T Todaka… - American journal …, 2003 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Our preliminary report on intrathecal urokinase (UK)
infusion into the cisterna magna (CM) with a microcatheter showed good results in terms of …

Microcatheter intrathecal urokinase infusion into cisterna magna for prevention of cerebral vasospasm: preliminary report

J Hamada, T Mizuno, Y Kai, M Morioka, Y Ushio - Stroke, 2000 - Am Heart Assoc
Background and Purpose—The feasibility of preventing vasospasm by intrathecal
anterograde infusion of urokinase (UK) into the cisterna magna was studied in patients with …

Single blood injection into the ventral cisterna magna through a microcatheter for the production of delayed cerebral vasospasm: experimental study in dogs

T Mizuno, J Hamada, Y Kai, T Todaka… - American journal …, 2003 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: We developed an experimental canine subarachnoid
hemorrhage (SAH) model in which one-time blood injection by means of a microcatheter …

Effect on cerebral vasospasm of coil embolization followed by microcatheter intrathecal urokinase infusion into the cisterna magna: a prospective randomized study

J Hamada, Y Kai, M Morioka, S Yano, T Mizuno… - Stroke, 2003 - Am Heart Assoc
Background and Purpose—Vasospasm remains the leading cause of death and permanent
neurological disability in patients with aneurysmal subarachnoid hemorrhage (SAH). The …

Urokinase cisternal irrigation therapy for prevention of symptomatic vasospasm after aneurysmal subarachnoid hemorrhage: a study of urokinase concentration and …

T Sasaki, N Kodama, M Kawakami, M Sato, J Asari… - Stroke, 2000 - Am Heart Assoc
Background and Purpose—Cisternal irrigation therapy with urokinase (UK) was performed
in multiple institutions to prevent symptomatic vasospasm. The efficacy and safety of this …

Comparison of intrathecal administration of urokinase and tissue plasminogen activator on subarachnoid clot and chronic vasospasm in a primate model

GB Hariton, JM Findlay, BKA Weir, H Kasuya… - …, 1993 - journals.lww.com
Abstract SAFETY AND EFFICACY of the thrombolytic agent urokinase (URO) in the
elimination of subarachnoid clot and prevention of chronic vasospasm was compared with …

Selective intraarterial nimodipine treatment in an experimental subarachnoid hemorrhage model

MM Firat, V Gelebek, HS Orer… - American journal …, 2005 - Am Soc Neuroradiology
BACKROUND AND PURPOSE: Cerebral vasospasm secondary to subarachnoid
hemorrhage (SAH) has been a serious clinical problem. The aim of the present study is to …

Prospective study on the prevention of cerebral vasospasm by intrathecal fibrinolytic therapy with tissue-type plasminogen activator

K MIzoI, T Yoshimoto, A Takahashi, S Fujiwara… - Journal of …, 1993 - thejns.org
✓ The authors have evaluated the efficacy of postoperative intrathecal injections of tissue-
type plasminogen activator (tPA) in preventing cerebral vasospasm in patients with a diffuse …

Efficacy of low-dose tissue-plasminogen activator intracisternal administration for the prevention of cerebral vasospasm after subarachnoid hemorrhage

T Yamamoto, T Esaki, Y Nakao, K Mori - World neurosurgery, 2010 - Elsevier
BACKGROUND: Vasospasm is one of the important factors associated with the functional
prognosis after subarachnoid hemorrhage (SAH). Intracisternal administration of …

[HTML][HTML] Ultrasound guided double injection of blood into cisterna magna: a rabbit model for treatment of cerebral vasospasm

Y Chen, Y Zhu, Y Zhang, Z Zhang, J Lian, F Luo… - BioMedical Engineering …, 2016 - Springer
Background Double injection of blood into cisterna magna using a rabbit model results in
cerebral vasospasm. An unacceptably high mortality rate tends to limit the application of …