Histone modifications and chromatin-associated protein complexes are crucially involved in
the control of gene expression, supervising cell fate decisions and differentiation. Many …

In pluripotent stem cells, the interplay between signaling cues, epigenetic regulators and
transcription factors orchestrates developmental potency. Flexibility in gene expression control …

Prmt5, an arginine methyltransferase, has multiple roles in germ cells, and possibly in
pluripotency. Here we show that loss of Prmt5 function is early embryonic-lethal due to the …

Gene expression requires successful communication between enhancer and promoter
regions, whose activities are regulated by a variety of factors and associated with distinct …

Erk1/2 activation contributes to mouse ES cell pluripotency. We found a direct role of Erk1/2
in modulating chromatin features required for regulated developmental gene expression. …

This paper presents a study of the near-mirror-finish phenomenon in electrical discharge
machining (EDM) when fine powder is introduced into the dielectric fluid as a suspension at the …

Background and Purpose Cigarette smoke is a major cause for chronic obstructive pulmonary
disease ( COPD ). Andrographolide is an active biomolecule isolated from the plant A …

… where w max and w min are the bounds on inertia weight, t is the number of iteration, and
T max is the maximum number of iteration. The w max and w min were fixed at 0.9 and 0.4, …

A cytotoxin produced by some Helicobacter pylori strains has recently been identified. The
cytotoxin induces intracellular vacuolization of cultured cells. The aim of the present study …

The omnipresence of allosteric regulation together with the fundamental role of structural
dynamics in this phenomenon have initiated a great interest to the detection of regulatory …