User profiles for X. Urra

Xabier Urra

Head of Neurology, Hospital Clínic Barcelona
Verified email at clinic.cat
Cited by 15720

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation

Á Chamorro, U Dirnagl, X Urra, AM Planas - The Lancet Neurology, 2016 - thelancet.com
Treatments for acute ischaemic stroke continue to evolve after the superior value of endovascular
thrombectomy was confirmed over systemic thrombolysis. Unfortunately, numerous …

The immunology of acute stroke

A Chamorro, A Meisel, AM Planas, X Urra… - Nature reviews …, 2012 - nature.com
Recent clinical and experimental studies have highlighted a complex role for the immune
system in the pathophysiological changes that occur after acute stroke. Sensors of the innate …

Infection after acute ischemic stroke: a manifestation of brain-induced immunodepression

A Chamorro, X Urra, AM Planas - Stroke, 2007 - Am Heart Assoc
… Xabier Urra … Further, acute respiratory infection with “normal” chest x-rays may indicate
pneumonia in about 30% of the cases, if a high resolution lung tomography is performed. …

[HTML][HTML] Thrombectomy within 8 hours after symptom onset in ischemic stroke

…, S Abilleira, M Ribó, M Millán, X Urra… - … England Journal of …, 2015 - Mass Medical Soc
Background We aimed to assess the safety and efficacy of thrombectomy for the treatment
of stroke in a trial embedded within a population-based stroke reperfusion registry. Methods …

Thrombectomy for anterior circulation stroke beyond 6 h from time last known well (AURORA): a systematic review and individual patient data meta-analysis

…, JJ Heit, BK Menon, S Kemp, R Budzik, X Urra… - The Lancet, 2022 - thelancet.com
Background Trials examining the benefit of thrombectomy in anterior circulation proximal
large vessel occlusion stroke have enrolled patients considered to have salvageable brain …

Acute stroke care is at risk in the era of COVID-19: experience at a comprehensive stroke center in Barcelona

…, M Vargas, A Renú, L Llull, V Obach, S Amaro, X Urra… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: The purpose of the study is to analyze how the coronavirus disease
2019 (COVID-19) pandemic affected acute stroke care in a Comprehensive Stroke Center…

Neutrophil recruitment to the brain in mouse and human ischemic stroke

…, E Gelpi, J Pedragosa, C Justicia, X Urra… - Acta …, 2015 - Springer
Neutrophils are rapidly recruited in response to local tissue infection or inflammation. Stroke
triggers a strong inflammatory reaction but the relevance of neutrophils in the ischemic brain …

Effect of direct transportation to thrombectomy-capable center vs local stroke center on neurological outcomes in patients with suspected large-vessel occlusion stroke …

…, TG Jovin, Á García-Tornel, X Jimenez, X Urra… - Jama, 2022 - jamanetwork.com
Importance In nonurban areas with limited access to thrombectomy-capable centers, optimal
prehospital transport strategies in patients with suspected large-vessel occlusion stroke are …

Effect of intra-arterial alteplase vs placebo following successful thrombectomy on functional outcomes in patients with large vessel occlusion acute ischemic stroke: the …

…, M Terceño, S Amaro, J Serena, X Urra… - Jama, 2022 - jamanetwork.com
Importance It is estimated that only 27% of patients with acute ischemic stroke and large
vessel occlusion who undergo successful reperfusion after mechanical thrombectomy are …

Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a …

…, SM Davis, O Jansen, M Rubiera, X Urra… - The Lancet …, 2018 - thelancet.com
Background General anaesthesia (GA) during endovascular thrombectomy has been
associated with worse patient outcomes in observational studies compared with patients treated …