Subarachnoid haemorrhage (SAH) is a subtype of stroke caused by the rupture of an
intracranial aneurysm. Genetic factors play an important part in the pathogenesis of SAH and …

Methods We conducted a systematic review and meta-analysis of studies reporting
circulating IL-6 in AAA, and new investigations of the association between a common non-…

… Ruigrok was supported by a clinical fellowship grant by the Netherlands Organization for
Scientific Research (NOW; project no. 40-00703-98-13533). The authors have no personal, …

… Ynte M Ruigrok … YM Ruigrok was supported by a grant from the Dr. E. Dekker program
of the Netherlands Heart Foundation (2005T014). … Gabriel JE Rinkel & Ynte M Ruigrok …

Saccular intracranial aneurysms are balloon-like dilations of the intracranial arterial wall;
their hemorrhage commonly results in severe neurologic impairment and death. We report a …

Rupture of an intracranial aneurysm leads to subarachnoid hemorrhage, a severe type of
stroke. To discover new risk loci and the genetic architecture of intracranial aneurysms, we …

Stroke is the world's third leading cause of death. One cause of stroke, intracranial aneurysm,
affects ∼2% of the population and accounts for 500,000 hemorrhagic strokes annually in …

We performed a genome-wide association study on 1,292 individuals with abdominal aortic
aneurysms (AAAs) and 30,503 controls from Iceland and The Netherlands, with a follow-up …

Evidence suggests that statin therapy reduces the risk of stroke in patients with coronary heart
disease (CHD), but its benefit for patients with cerebrovascular disease and no history of …

Objectives : The purpose of this study is investigate the effects of variants in the
apolipoprotein(a) gene (LPA) on vascular diseases with different atherosclerotic and thrombotic …