Although the diagnosis of dementia is still largely a clinical one, based on history and disease
course, neuroimaging has dramatically increased our ability to accurately diagnose it. …

Background: Amyloid-ß (Aß) and tau protein accumulation in the brain is thought to be one
of the causes of Alzheimer’s disease (AD). Recent study found that the glymphatic system …

Background: In clinical practice, equivocal findings are inevitable in visual interpretation of
whether amyloid positron emission tomography (PET) is positive or negative. It is therefore …

Introduction The molecular mechanism of neurodegeneration, including tau and neurite
complexity, is an important topic in Alzheimer's disease (AD) research. Methods We recruited 27 …

Introduction: Tau protein accumulation in the brain is thought to be one of the causes of
progressive supranuclear palsy (PSP). The glymphatic system was discovered a decade ago as …

Introduction Free‐water (FW) imaging, a new analysis method for diffusion magnetic resonance
imaging (MRI), can indicate neuroinflammation and degeneration. We evaluated FW in …

Recent developments in image analysis have enabled an individual’s brain network to be
evaluated and brain age to be predicted from gray matter images. Our study aimed to …

In multiple system atrophy with predominant parkinsonism (MSA-P), several voxel-based
morphometry (VBM) studies have revealed gray matter loss; however, the white matter volume …

Objective Amyloid positron emission tomography (PET) can reliably detect senile plaques
and fluorinated ligands are approved for clinical use. However, the clinical impact of amyloid …

Objective: In this study, we investigated the ability of fluid-attenuated inversion recovery (FLAIR)
data coupled with machine-leaning algorithms to differentiate normal and epileptic …